Molecular mechanisms of the effects of N-ethylmaleimide and 1,4-dithioerythritol on regulation of apoptosis in P19 cells under hypoxia

Relevance. Impairment of apoptosis regulation in P19 cells is correlated with generation of oxidative stress. Under hypoxia, changes in mitochondrial functions occur, which may exacerbate oxidative stress in the tumor cell. The aim of the study was to evaluate the effects of N-ethylmaleimide and 1,4...

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Bibliographic Details
Main Authors: O. L. Nosareva, D. S. Orlov, E. V. Shakhristova, E. A. Stepovaya
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2020-07-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/2863