Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study
Bacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular p...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2019-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800013C.pdf |
| _version_ | 1828524849209802752 |
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| author | Ćetković Dejan Milić Marija S. Biočanin Vladimir Brajić Ivana Ćalasan Dejan Radović Katarina Živković Rade Brković Božidar |
| author_facet | Ćetković Dejan Milić Marija S. Biočanin Vladimir Brajić Ivana Ćalasan Dejan Radović Katarina Živković Rade Brković Božidar |
| author_sort | Ćetković Dejan |
| collection | DOAJ |
| description | Bacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular parameters after the anterior middle superior alveolar (AMSA) nerve block with 4% articaine with epinephrine administered by conventional cartridge-syringe and computer- controlled local anesthetic delivery system (CCLADS). Methods. This controlled double-blind cross-over randomized clinical study included 38 healthy volunteers. Efficacy of pulpal anesthesia after the AMSA nerve block was evaluated by measuring a success rate, onset and duration of pulpal anesthesia, using an electrical pulp tester. The parameters of cardiovascular function (systolic and diastolic blood pressure, heart rate) were monitored noninvasively. Results. Successful pulpal anesthesia of all tested teeth was obtained in 57.9% participants with CCLADS and in 44.7% participants with conventional syringe. The onset time was not significantly different between two investigated groups. The pulpal anesthesia duration was not significantly different neither within nor between investigated groups. The systolic and diastolic blood pressures were significantly decreased in both investigated groups, in comparison with the baseline values. Heart rate significantly decreased within CCLADS from 10th to 30th minute when compared to baseline. Conclusion. The efficacy of pulpal anesthesia and safety of cardiovascular profile of 0.6 mL of articaine with epinephrine (1:100.000) delivered with CCLADS were improved in comparison to the conventional syringe delivery. Significant changes of cardiovascular function were not observed. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 175021] |
| first_indexed | 2024-12-11T20:55:14Z |
| format | Article |
| id | doaj.art-c8283f9bb094434083fd750d2f78ba37 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-12-11T20:55:14Z |
| publishDate | 2019-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-c8283f9bb094434083fd750d2f78ba372022-12-22T00:51:08ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202019-01-0176101045105310.2298/VSP170511013C0042-84501800013CEfficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical studyĆetković Dejan0Milić Marija S.1Biočanin Vladimir2Brajić Ivana3Ćalasan Dejan4Radović Katarina5Živković Rade6Brković Božidar7University of Belgrade, Faculty of Dental Medicine, Institute of Anatomy, Belgrade, SerbiaUniversity of Belgrade, Faculty of Dental Medicine, Oral Surgery Clinic, Belgrade, SerbiaFaculty of Pharmacy and Health Sciences, Travnik, Bosnia and Herzegovina University of Belgrade, Faculty of Dental Medicine, Oral Surgery Clinic, Belgrade, SerbiaUniversity of Belgrade, Faculty of Dental Medicine, Oral Surgery Clinic, Belgrade, SerbiaUniversity of Belgrade, Faculty of Dental Medicine, Prosthodontics Clinic, Belgrade, SerbiaUniversity of Belgrade, Faculty of Dental Medicine, Prosthodontics Clinic, Belgrade, SerbiaUniversity of Belgrade, Faculty of Dental Medicine, Oral Surgery Clinic, Belgrade, SerbiaBacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular parameters after the anterior middle superior alveolar (AMSA) nerve block with 4% articaine with epinephrine administered by conventional cartridge-syringe and computer- controlled local anesthetic delivery system (CCLADS). Methods. This controlled double-blind cross-over randomized clinical study included 38 healthy volunteers. Efficacy of pulpal anesthesia after the AMSA nerve block was evaluated by measuring a success rate, onset and duration of pulpal anesthesia, using an electrical pulp tester. The parameters of cardiovascular function (systolic and diastolic blood pressure, heart rate) were monitored noninvasively. Results. Successful pulpal anesthesia of all tested teeth was obtained in 57.9% participants with CCLADS and in 44.7% participants with conventional syringe. The onset time was not significantly different between two investigated groups. The pulpal anesthesia duration was not significantly different neither within nor between investigated groups. The systolic and diastolic blood pressures were significantly decreased in both investigated groups, in comparison with the baseline values. Heart rate significantly decreased within CCLADS from 10th to 30th minute when compared to baseline. Conclusion. The efficacy of pulpal anesthesia and safety of cardiovascular profile of 0.6 mL of articaine with epinephrine (1:100.000) delivered with CCLADS were improved in comparison to the conventional syringe delivery. Significant changes of cardiovascular function were not observed. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 175021]http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800013C.pdfarticaineanesthesia dentalanesthesia, localtherapy, computer assistednerve block injections |
| spellingShingle | Ćetković Dejan Milić Marija S. Biočanin Vladimir Brajić Ivana Ćalasan Dejan Radović Katarina Živković Rade Brković Božidar Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study Vojnosanitetski Pregled articaine anesthesia dental anesthesia, local therapy, computer assisted nerve block injections |
| title | Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study |
| title_full | Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study |
| title_fullStr | Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study |
| title_full_unstemmed | Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study |
| title_short | Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer-controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study |
| title_sort | efficacy and safety of 4 articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery prospective randomized cross over clinical study |
| topic | articaine anesthesia dental anesthesia, local therapy, computer assisted nerve block injections |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800013C.pdf |
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