Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation

Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation

Introduction: We aimed to demonstrate non-invasive measurements of regional oxygen extraction fraction (OEF) from quantitative BOLD MRI modeling at baseline and after pharmacological vasodilation. We hypothesized that OEF decreases in response to vasodilation with acetazolamide (ACZ) in healthy cond...

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Bibliographic Details
Main Authors: Linh N. N. Le, Gregory J. Wheeler, Emily N. Holy, Corinne A. Donnay, Nicholas P. Blockley, Alan H. Yee, Kwan L. Ng, Audrey P. Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Physiology
Subjects:
Oxygen extraction fraction (OEF)
cerebral blood flow (CBF)
vasodilation
arterial spin labeling (ASL) MRI
quantitative BOLD (qBOLD)
magnetic resonance imaging (MRI)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1231793/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1231793/full

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