A radiation-related second primary gastrointestinal stromal tumor in the bladder
Abstract. A 69-year-old man underwent 78 Gy/39 Fr of intensity-modulated radiation therapy for prostate cancer. Seven years after radiotherapy, a nonpapillary bladder tumor was identified. Transurethral resection of the bladder tumor was performed, and the pathological diagnosis was spindle cell sar...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Health
2023-12-01
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| Series: | Current Urology |
| Online Access: | http://journals.lww.com/10.1097/CU9.0000000000000186 |
| _version_ | 1827631803463106560 |
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| author | Mai Hori Kazuki Maki Yumiko Okuno Koji Mikami Takumi Takeuchi |
| author_facet | Mai Hori Kazuki Maki Yumiko Okuno Koji Mikami Takumi Takeuchi |
| author_sort | Mai Hori |
| collection | DOAJ |
| description | Abstract. A 69-year-old man underwent 78 Gy/39 Fr of intensity-modulated radiation therapy for prostate cancer. Seven years after radiotherapy, a nonpapillary bladder tumor was identified. Transurethral resection of the bladder tumor was performed, and the pathological diagnosis was spindle cell sarcoma. Immunostaining revealed KIT−, DOG1++, CD34−, Actin++, Cytokeratin−, Desmin−, S100 protein−, and Vimentin++. No tumor recurrence was observed until 17 months after tumor resection. DOG1 is strongly and specifically expressed in gastrointestinal stromal tumors. This was a rare case of bladder gastrointestinal stromal tumor as a radiation-related second primary tumor. |
| first_indexed | 2024-03-09T14:27:13Z |
| format | Article |
| id | doaj.art-c829e46b1f184f6f860dadab1434c152 |
| institution | Directory Open Access Journal |
| issn | 1661-7649 |
| language | English |
| last_indexed | 2024-03-09T14:27:13Z |
| publishDate | 2023-12-01 |
| publisher | Wolters Kluwer Health |
| record_format | Article |
| series | Current Urology |
| spelling | doaj.art-c829e46b1f184f6f860dadab1434c1522023-11-28T07:08:48ZengWolters Kluwer HealthCurrent Urology1661-76492023-12-0117426827010.1097/CU9.0000000000000186202312000-00008A radiation-related second primary gastrointestinal stromal tumor in the bladderMai Hori0Kazuki Maki1Yumiko Okuno2Koji Mikami3Takumi Takeuchi4Department of Urology, Japan Organization of Occupational Health and Safety, Kanto Rosai Hospital, Kawasaki, JapanDepartment of Urology, Japan Organization of Occupational Health and Safety, Kanto Rosai Hospital, Kawasaki, JapanDepartment of Urology, Japan Organization of Occupational Health and Safety, Kanto Rosai Hospital, Kawasaki, JapanDepartment of Urology, Japan Organization of Occupational Health and Safety, Kanto Rosai Hospital, Kawasaki, JapanDepartment of Urology, Japan Organization of Occupational Health and Safety, Kanto Rosai Hospital, Kawasaki, JapanAbstract. A 69-year-old man underwent 78 Gy/39 Fr of intensity-modulated radiation therapy for prostate cancer. Seven years after radiotherapy, a nonpapillary bladder tumor was identified. Transurethral resection of the bladder tumor was performed, and the pathological diagnosis was spindle cell sarcoma. Immunostaining revealed KIT−, DOG1++, CD34−, Actin++, Cytokeratin−, Desmin−, S100 protein−, and Vimentin++. No tumor recurrence was observed until 17 months after tumor resection. DOG1 is strongly and specifically expressed in gastrointestinal stromal tumors. This was a rare case of bladder gastrointestinal stromal tumor as a radiation-related second primary tumor.http://journals.lww.com/10.1097/CU9.0000000000000186 |
| spellingShingle | Mai Hori Kazuki Maki Yumiko Okuno Koji Mikami Takumi Takeuchi A radiation-related second primary gastrointestinal stromal tumor in the bladder Current Urology |
| title | A radiation-related second primary gastrointestinal stromal tumor in the bladder |
| title_full | A radiation-related second primary gastrointestinal stromal tumor in the bladder |
| title_fullStr | A radiation-related second primary gastrointestinal stromal tumor in the bladder |
| title_full_unstemmed | A radiation-related second primary gastrointestinal stromal tumor in the bladder |
| title_short | A radiation-related second primary gastrointestinal stromal tumor in the bladder |
| title_sort | radiation related second primary gastrointestinal stromal tumor in the bladder |
| url | http://journals.lww.com/10.1097/CU9.0000000000000186 |
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