Secondary prevention of sudden cardiac death
The prevention and treatment of sudden cardiac death (SCD) remains a significant public health challenge. For patients with a history of sudden death attributable to ventricular arrhythmia, implantable cardioverter-defibrillator (ICD) therapy is a mainstay of treatment, although these patients remai...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-10-01
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| Series: | Heart Rhythm O2 |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666501820301112 |
| _version_ | 1818738153219948544 |
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| author | Neal A. Chatterjee, MD, MSc Thomas D. Rea, MD, MPH |
| author_facet | Neal A. Chatterjee, MD, MSc Thomas D. Rea, MD, MPH |
| author_sort | Neal A. Chatterjee, MD, MSc |
| collection | DOAJ |
| description | The prevention and treatment of sudden cardiac death (SCD) remains a significant public health challenge. For patients with a history of sudden death attributable to ventricular arrhythmia, implantable cardioverter-defibrillator (ICD) therapy is a mainstay of treatment, although these patients remain at high risk for recurrent ventricular arrhythmia and defibrillator therapies. In this review, we summarize landmark clinical trials evaluating the efficacy of ICD therapy in secondary prevention patients, review clinical outcomes including mode of death in survivors of SCD, and highlight the role for systematic diagnostic evaluation. We additionally discuss the invasive electrophysiological management of these patients, including ICD selection and programming as well as the role and timing of antiarrhythmic drug therapy and catheter ablation. Finally, we frame future challenges and needs to advance the care for secondary prevention patients. |
| first_indexed | 2024-12-18T01:04:24Z |
| format | Article |
| id | doaj.art-c82a1ca4b5304257a963b0c2fbc27522 |
| institution | Directory Open Access Journal |
| issn | 2666-5018 |
| language | English |
| last_indexed | 2024-12-18T01:04:24Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heart Rhythm O2 |
| spelling | doaj.art-c82a1ca4b5304257a963b0c2fbc275222022-12-21T21:26:16ZengElsevierHeart Rhythm O22666-50182020-10-0114297310Secondary prevention of sudden cardiac deathNeal A. Chatterjee, MD, MSc0Thomas D. Rea, MD, MPH1Electrophysiology Section, Cardiology Division, University of Washington, Seattle, Washington; Address reprint requests and correspondence: Dr Neal A. Chatterjee, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195.Division of General Internal Medicine, University of Washington, Seattle, WashingtonThe prevention and treatment of sudden cardiac death (SCD) remains a significant public health challenge. For patients with a history of sudden death attributable to ventricular arrhythmia, implantable cardioverter-defibrillator (ICD) therapy is a mainstay of treatment, although these patients remain at high risk for recurrent ventricular arrhythmia and defibrillator therapies. In this review, we summarize landmark clinical trials evaluating the efficacy of ICD therapy in secondary prevention patients, review clinical outcomes including mode of death in survivors of SCD, and highlight the role for systematic diagnostic evaluation. We additionally discuss the invasive electrophysiological management of these patients, including ICD selection and programming as well as the role and timing of antiarrhythmic drug therapy and catheter ablation. Finally, we frame future challenges and needs to advance the care for secondary prevention patients.http://www.sciencedirect.com/science/article/pii/S2666501820301112Cardiac arrestEpidemiologyImplantable cardioverter-defibrillatorPreventionSudden deathVentricular arrhythmia |
| spellingShingle | Neal A. Chatterjee, MD, MSc Thomas D. Rea, MD, MPH Secondary prevention of sudden cardiac death Heart Rhythm O2 Cardiac arrest Epidemiology Implantable cardioverter-defibrillator Prevention Sudden death Ventricular arrhythmia |
| title | Secondary prevention of sudden cardiac death |
| title_full | Secondary prevention of sudden cardiac death |
| title_fullStr | Secondary prevention of sudden cardiac death |
| title_full_unstemmed | Secondary prevention of sudden cardiac death |
| title_short | Secondary prevention of sudden cardiac death |
| title_sort | secondary prevention of sudden cardiac death |
| topic | Cardiac arrest Epidemiology Implantable cardioverter-defibrillator Prevention Sudden death Ventricular arrhythmia |
| url | http://www.sciencedirect.com/science/article/pii/S2666501820301112 |
| work_keys_str_mv | AT nealachatterjeemdmsc secondarypreventionofsuddencardiacdeath AT thomasdreamdmph secondarypreventionofsuddencardiacdeath |