The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study
Abstract Background: Oxidative stress contributes to the development of cardiovascular disease. Tools for evaluating the anti-inflammatory and antioxidative characteristics of an individual’s diet as a whole may be valuable for assessing the combined effects of dietary antioxidants on health....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-12-01
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| Series: | Journal of Biostatistics and Epidemiology |
| Subjects: | |
| Online Access: | https://jbe.tums.ac.ir/index.php/jbe/article/view/1102 |
| _version_ | 1797742554165280768 |
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| author | Parisa Keshani Maryam Jalali Masoumeh Ghoddusi Johari Ramin Rezaeianzadeh Seyed Vahid Hosseini Abbas Rezaianzadeh |
| author_facet | Parisa Keshani Maryam Jalali Masoumeh Ghoddusi Johari Ramin Rezaeianzadeh Seyed Vahid Hosseini Abbas Rezaianzadeh |
| author_sort | Parisa Keshani |
| collection | DOAJ |
| description |
Abstract
Background:
Oxidative stress contributes to the development of cardiovascular disease. Tools for evaluating the anti-inflammatory and antioxidative characteristics of an individual’s diet as a whole may be valuable for assessing the combined effects of dietary antioxidants on health. This population-based study aimed to investigate the association between dietary antioxidants and cardiac disease.
Methods:
In this population-based cross-sectional study, 10439 individuals aged 40-70 years were recruited during 2014-2017 in Kherameh cohort study which is a part of the Prospective Epidemiological Research Studies in Iran (PERSIAN). The food frequency questionnaire (FFQ) with 130 food items was used to assess the dietary intakes. Vitamin A, E, C, selenium, zinc and Manganese intakes were used to compute dietary antioxidant index (DAI) and dietary antioxidant quality score (DAQs).
Results:
The participants’ mean age was 52.1± 8.3 years. Among all, 4356 (41.7%) were overweight and 1892 (18.1%) were obese. According to the results, odds of cardiac diseases decreased by increasing DAI score (OR=0.80, Pvalue <0.001). , Odds of cardiac diseases increased by lower DAQS after adjusting for demographic variables including age, sex, BMI, Marital status and hypertension (OR=0.799, P value=0.002)
Conclusion:
The role of anti-oxidants in reducing the odds of cardiovascular disease is very important. Our results highlighted that DAQS and DAI had protective effect on the odds of cardiovascular disease. Therefore, it is suggested that anti-oxidants as zinc, manganese, selenium, and vitamins A, E and C should be taken through food to reduce the risk of the disease.
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| first_indexed | 2024-03-12T14:42:21Z |
| format | Article |
| id | doaj.art-c82abae1eeb54a43a189ae5680c50a44 |
| institution | Directory Open Access Journal |
| issn | 2383-4196 2383-420X |
| language | English |
| last_indexed | 2024-03-12T14:42:21Z |
| publishDate | 2022-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Biostatistics and Epidemiology |
| spelling | doaj.art-c82abae1eeb54a43a189ae5680c50a442023-08-16T06:12:40ZengTehran University of Medical SciencesJournal of Biostatistics and Epidemiology2383-41962383-420X2022-12-018410.18502/jbe.v8i4.13358The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort StudyParisa Keshani0Maryam Jalali1Masoumeh Ghoddusi Johari2Ramin Rezaeianzadeh3Seyed Vahid Hosseini4Abbas Rezaianzadeh51 Colorectal Research Center, Shiraz University of Medical Sciences. Shiraz, Iran.Colorectal Research Center, Shiraz University of Medical Sciences. Shiraz, Iran.Breast Diseases Research Center, Shiraz University of Medical Sciences. Shiraz, Iran.Experimental Medicine Program, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaColorectal Research Center, Shiraz University of Medical Sciences. Shiraz, Iran.Colorectal Research Center, Shiraz University of Medical Sciences. Shiraz, Iran. Abstract Background: Oxidative stress contributes to the development of cardiovascular disease. Tools for evaluating the anti-inflammatory and antioxidative characteristics of an individual’s diet as a whole may be valuable for assessing the combined effects of dietary antioxidants on health. This population-based study aimed to investigate the association between dietary antioxidants and cardiac disease. Methods: In this population-based cross-sectional study, 10439 individuals aged 40-70 years were recruited during 2014-2017 in Kherameh cohort study which is a part of the Prospective Epidemiological Research Studies in Iran (PERSIAN). The food frequency questionnaire (FFQ) with 130 food items was used to assess the dietary intakes. Vitamin A, E, C, selenium, zinc and Manganese intakes were used to compute dietary antioxidant index (DAI) and dietary antioxidant quality score (DAQs). Results: The participants’ mean age was 52.1± 8.3 years. Among all, 4356 (41.7%) were overweight and 1892 (18.1%) were obese. According to the results, odds of cardiac diseases decreased by increasing DAI score (OR=0.80, Pvalue <0.001). , Odds of cardiac diseases increased by lower DAQS after adjusting for demographic variables including age, sex, BMI, Marital status and hypertension (OR=0.799, P value=0.002) Conclusion: The role of anti-oxidants in reducing the odds of cardiovascular disease is very important. Our results highlighted that DAQS and DAI had protective effect on the odds of cardiovascular disease. Therefore, it is suggested that anti-oxidants as zinc, manganese, selenium, and vitamins A, E and C should be taken through food to reduce the risk of the disease. https://jbe.tums.ac.ir/index.php/jbe/article/view/1102Keywords: AntioxidantsCardiac diseaseDietary intakeDietary antioxidant indexDietary antioxidant quality |
| spellingShingle | Parisa Keshani Maryam Jalali Masoumeh Ghoddusi Johari Ramin Rezaeianzadeh Seyed Vahid Hosseini Abbas Rezaianzadeh The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study Journal of Biostatistics and Epidemiology Keywords: Antioxidants Cardiac disease Dietary intake Dietary antioxidant index Dietary antioxidant quality |
| title | The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study |
| title_full | The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study |
| title_fullStr | The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study |
| title_full_unstemmed | The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study |
| title_short | The Association between Dietary Antioxidant Indices and Cardiac Disease: Baseline Data of Kharameh Cohort Study |
| title_sort | association between dietary antioxidant indices and cardiac disease baseline data of kharameh cohort study |
| topic | Keywords: Antioxidants Cardiac disease Dietary intake Dietary antioxidant index Dietary antioxidant quality |
| url | https://jbe.tums.ac.ir/index.php/jbe/article/view/1102 |
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