Ventral tegmental area astrocytes orchestrate avoidance and approach behavior
Astrocytes can dynamically control glutamate availability at specific active synapses through the glutamate transporter, GLT-1. Here, the authors show that astrocytes in the VTA selectively facilitate excitation of VTA GABAergic neurons to inhibit dopamine neurons and drive avoidance behavior via GL...
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Bibliographic Details
Main Authors: |
J. A. Gomez,
J. M. Perkins,
G. M. Beaudoin,
N. B. Cook,
S. A. Quraishi,
E. A. Szoeke,
K. Thangamani,
C. W. Tschumi,
M. J. Wanat,
A. M. Maroof,
M. J. Beckstead,
P. A. Rosenberg,
C. A. Paladini |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2019-03-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-019-09131-y
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