A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser
<title>ABSTRACT</title><sec><title>Introduction:</title><p>The treatment of pelvic malignancies with radiotherapy can develop severe sequelae, especially radiation-induced hemorrhagic cystitis. It is a progressive disease that can lead to the need for blood transf...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Urologia
2015-06-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382015000300584&lng=en&tlng=en |
| _version_ | 1828823912866119680 |
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| author | Daniel Roberto Martinez Cesar E Ercole Juan Gabriel Lopez Justin Parker Mary K Hall |
| author_facet | Daniel Roberto Martinez Cesar E Ercole Juan Gabriel Lopez Justin Parker Mary K Hall |
| author_sort | Daniel Roberto Martinez |
| collection | DOAJ |
| description | <title>ABSTRACT</title><sec><title>Introduction:</title><p>The treatment of pelvic malignancies with radiotherapy can develop severe sequelae, especially radiation-induced hemorrhagic cystitis. It is a progressive disease that can lead to the need for blood transfusion, hospitalizations, and surgical interventions. This tends to affect the quality of life of these patients, and management can at times be difficult. We have evaluated the GreenLight Xcelerated Performance System (XPS) with TruCoag, although primarily used for management of benign prostatic hypertrophy (BPH), for the treatment of radiation-induced hemorrhagic cystitis.</p></sec><sec><title>Materials and Methods:</title><p>After International Review Board (IRB) approval, a retrospective chart review was performed in addition to a literature search. A series of four male patients, mean age of 81 years, with radiation-induced hemorrhagic cystitis secondary to radiotherapy for pelvic malignancies (3 prostate cancer, 1 rectal cancer) were successfully treated with the GreenLight laser after unsuccessful treatment with current therapies described in the literature.</p></sec><sec><title>Results:</title><p>All four patients treated with the GreenLight laser had resolution of their hematuria after one treatment and were discharge from the hospital with clear urine.</p></sec><sec><title>Conclusion:</title><p>The GreenLight XPS laser shows promising results for the treatment of patients with radiation-induced hemorrhagic cystitis, and deserves further evaluation and validation, especially since there is limited data available in the literature regarding the use of this technology for the treatment of this devastating condition.</p></sec> |
| first_indexed | 2024-12-12T13:44:59Z |
| format | Article |
| id | doaj.art-c8348ccd22344088af9d71037224f78a |
| institution | Directory Open Access Journal |
| issn | 1677-6119 |
| language | English |
| last_indexed | 2024-12-12T13:44:59Z |
| publishDate | 2015-06-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-c8348ccd22344088af9d71037224f78a2022-12-22T00:22:42ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192015-06-0141358458710.1590/S1677-5538.IBJU.2014.0411S1677-55382015000300584A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS LaserDaniel Roberto MartinezCesar E ErcoleJuan Gabriel LopezJustin ParkerMary K Hall<title>ABSTRACT</title><sec><title>Introduction:</title><p>The treatment of pelvic malignancies with radiotherapy can develop severe sequelae, especially radiation-induced hemorrhagic cystitis. It is a progressive disease that can lead to the need for blood transfusion, hospitalizations, and surgical interventions. This tends to affect the quality of life of these patients, and management can at times be difficult. We have evaluated the GreenLight Xcelerated Performance System (XPS) with TruCoag, although primarily used for management of benign prostatic hypertrophy (BPH), for the treatment of radiation-induced hemorrhagic cystitis.</p></sec><sec><title>Materials and Methods:</title><p>After International Review Board (IRB) approval, a retrospective chart review was performed in addition to a literature search. A series of four male patients, mean age of 81 years, with radiation-induced hemorrhagic cystitis secondary to radiotherapy for pelvic malignancies (3 prostate cancer, 1 rectal cancer) were successfully treated with the GreenLight laser after unsuccessful treatment with current therapies described in the literature.</p></sec><sec><title>Results:</title><p>All four patients treated with the GreenLight laser had resolution of their hematuria after one treatment and were discharge from the hospital with clear urine.</p></sec><sec><title>Conclusion:</title><p>The GreenLight XPS laser shows promising results for the treatment of patients with radiation-induced hemorrhagic cystitis, and deserves further evaluation and validation, especially since there is limited data available in the literature regarding the use of this technology for the treatment of this devastating condition.</p></sec>http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382015000300584&lng=en&tlng=enCystitisTherapeuticsLasersRadiotherapy |
| spellingShingle | Daniel Roberto Martinez Cesar E Ercole Juan Gabriel Lopez Justin Parker Mary K Hall A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser International Brazilian Journal of Urology Cystitis Therapeutics Lasers Radiotherapy |
| title | A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser |
| title_full | A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser |
| title_fullStr | A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser |
| title_full_unstemmed | A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser |
| title_short | A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLight<sup>™</sup> XPS Laser |
| title_sort | novel approach for the treatment of radiation induced hemorrhagic cystitis with the greenlight sup ™ sup xps laser |
| topic | Cystitis Therapeutics Lasers Radiotherapy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382015000300584&lng=en&tlng=en |
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