<it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia
<p>Abstract</p> <p>Background</p> <p>In Zambia, the presence of bovine tuberculosis in both wild and domestic animals has long been acknowledged and mutual transmission between them has been predicted without any direct evidence. Elucidation of the circulating <it>...
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| Format: | Article |
| Language: | English |
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BMC
2012-11-01
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| Series: | BMC Veterinary Research |
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| Online Access: | http://www.biomedcentral.com/1746-6148/8/221 |
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| author | Hang’ombe Mudenda B Munyeme Musso Nakajima Chie Fukushima Yukari Suzuki Haruka Matandiko Wigganson Ishii Akihiro Mweene Aaron S Suzuki Yasuhiko |
| author_facet | Hang’ombe Mudenda B Munyeme Musso Nakajima Chie Fukushima Yukari Suzuki Haruka Matandiko Wigganson Ishii Akihiro Mweene Aaron S Suzuki Yasuhiko |
| author_sort | Hang’ombe Mudenda B |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>In Zambia, the presence of bovine tuberculosis in both wild and domestic animals has long been acknowledged and mutual transmission between them has been predicted without any direct evidence. Elucidation of the circulating <it>Mycobacterium bovis</it> strains at wild and domestic animals interphase area in Zambia, where bovine tuberculosis was diagnosed in wildlife seemed to be important.</p> <p>Results</p> <p>A PCR identified 15 and 37 <it>M. bovis</it> isolates from lechwe and cattle, respectively. Spoligotype analysis revealed that <it>M. bovis</it> strains from lechwe and cattle in Kafue basin clustered into a major node SB0120, where isolates outside the Kafue basin clustered into different nodes of SB0131 and SB0948. The comparatively higher variety of strains in cattle compared to lechwe elucidated by Mycobacterial Interspersed Repetitive Units–Variable Number Tandem Repeats analyses are consistent with cattle being the probable source of <it>M. bovis</it> in wild and domestic animals interphase area in Zambia.</p> <p>Conclusions</p> <p>These results provide strong evidence of <it>M. bovis</it> strains transfer between cattle and lechwe, with the latter having developed into a sylvatic reservoir host.</p> |
| first_indexed | 2024-12-21T06:19:24Z |
| format | Article |
| id | doaj.art-c835e49e53eb4cd08ac1db98453f5c13 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-21T06:19:24Z |
| publishDate | 2012-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-c835e49e53eb4cd08ac1db98453f5c132022-12-21T19:13:19ZengBMCBMC Veterinary Research1746-61482012-11-018122110.1186/1746-6148-8-221<it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in ZambiaHang’ombe Mudenda BMunyeme MussoNakajima ChieFukushima YukariSuzuki HarukaMatandiko WiggansonIshii AkihiroMweene Aaron SSuzuki Yasuhiko<p>Abstract</p> <p>Background</p> <p>In Zambia, the presence of bovine tuberculosis in both wild and domestic animals has long been acknowledged and mutual transmission between them has been predicted without any direct evidence. Elucidation of the circulating <it>Mycobacterium bovis</it> strains at wild and domestic animals interphase area in Zambia, where bovine tuberculosis was diagnosed in wildlife seemed to be important.</p> <p>Results</p> <p>A PCR identified 15 and 37 <it>M. bovis</it> isolates from lechwe and cattle, respectively. Spoligotype analysis revealed that <it>M. bovis</it> strains from lechwe and cattle in Kafue basin clustered into a major node SB0120, where isolates outside the Kafue basin clustered into different nodes of SB0131 and SB0948. The comparatively higher variety of strains in cattle compared to lechwe elucidated by Mycobacterial Interspersed Repetitive Units–Variable Number Tandem Repeats analyses are consistent with cattle being the probable source of <it>M. bovis</it> in wild and domestic animals interphase area in Zambia.</p> <p>Conclusions</p> <p>These results provide strong evidence of <it>M. bovis</it> strains transfer between cattle and lechwe, with the latter having developed into a sylvatic reservoir host.</p>http://www.biomedcentral.com/1746-6148/8/221Bovine tuberculosisCattle<it>Mycobacterium bovis</it>StrainsWildlife<it>Kobus leche Kafuensis</it> |
| spellingShingle | Hang’ombe Mudenda B Munyeme Musso Nakajima Chie Fukushima Yukari Suzuki Haruka Matandiko Wigganson Ishii Akihiro Mweene Aaron S Suzuki Yasuhiko <it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia BMC Veterinary Research Bovine tuberculosis Cattle <it>Mycobacterium bovis</it> Strains Wildlife <it>Kobus leche Kafuensis</it> |
| title | <it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia |
| title_full | <it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia |
| title_fullStr | <it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia |
| title_full_unstemmed | <it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia |
| title_short | <it>Mycobacterium bovis</it> infection at the interface between domestic and wild animals in Zambia |
| title_sort | it mycobacterium bovis it infection at the interface between domestic and wild animals in zambia |
| topic | Bovine tuberculosis Cattle <it>Mycobacterium bovis</it> Strains Wildlife <it>Kobus leche Kafuensis</it> |
| url | http://www.biomedcentral.com/1746-6148/8/221 |
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