Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report
Monkeypox is an emerging zoonosis that has been declared a public health threat due to its spread outside of endemic areas. We present two cases of monkeypox: one involving a 39-year-old male patient living with HIV on antiretroviral therapy with detectable viraemia and a low CD4 count, and another...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-10-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X231204193 |
| _version_ | 1797662280850079744 |
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| author | Daniel Toshkov Ivanov Nina Stoyanova Yancheva Trifon Kostadinov Valkov |
| author_facet | Daniel Toshkov Ivanov Nina Stoyanova Yancheva Trifon Kostadinov Valkov |
| author_sort | Daniel Toshkov Ivanov |
| collection | DOAJ |
| description | Monkeypox is an emerging zoonosis that has been declared a public health threat due to its spread outside of endemic areas. We present two cases of monkeypox: one involving a 39-year-old male patient living with HIV on antiretroviral therapy with detectable viraemia and a low CD4 count, and another involving a 44-year-old male, negative for HIV, who visited our Diagnostic and Consultative Unit with a new-onset skin rash. Both individuals identify as men who have sex with men and had travelled abroad before the disease onset. One patient was hospitalised, while the other was treated as an outpatient with follow-up care. Both cases were managed conservatively due to the unavailability of tecovirimat in Bulgaria. We emphasise the importance of recognising and diagnosing monkeypox and the significance of HIV screening, as monkeypox could be considered an AIDS-defining condition in people living with HIV. Maintaining a high level of suspicion for new cases is essential, as instances of monkeypox continue to be reported in non-endemic countries. |
| first_indexed | 2024-03-11T18:57:52Z |
| format | Article |
| id | doaj.art-c83706651cab4b69bd0f371a2c1f4625 |
| institution | Directory Open Access Journal |
| issn | 2050-313X |
| language | English |
| last_indexed | 2024-03-11T18:57:52Z |
| publishDate | 2023-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj.art-c83706651cab4b69bd0f371a2c1f46252023-10-10T17:03:19ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2023-10-011110.1177/2050313X231204193Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case reportDaniel Toshkov Ivanov0Nina Stoyanova Yancheva1Trifon Kostadinov Valkov2Specialized Hospital for Active Treatment of Infectious and Parasitic Diseases “Prof. Ivan Kirov,” Sofia, BulgariaDepartment of Infectious Disease, Parasitology and Tropical Medicine, Medical University, Sofia, BulgariaDepartment of Infectious Disease, Parasitology and Tropical Medicine, Medical University, Sofia, BulgariaMonkeypox is an emerging zoonosis that has been declared a public health threat due to its spread outside of endemic areas. We present two cases of monkeypox: one involving a 39-year-old male patient living with HIV on antiretroviral therapy with detectable viraemia and a low CD4 count, and another involving a 44-year-old male, negative for HIV, who visited our Diagnostic and Consultative Unit with a new-onset skin rash. Both individuals identify as men who have sex with men and had travelled abroad before the disease onset. One patient was hospitalised, while the other was treated as an outpatient with follow-up care. Both cases were managed conservatively due to the unavailability of tecovirimat in Bulgaria. We emphasise the importance of recognising and diagnosing monkeypox and the significance of HIV screening, as monkeypox could be considered an AIDS-defining condition in people living with HIV. Maintaining a high level of suspicion for new cases is essential, as instances of monkeypox continue to be reported in non-endemic countries.https://doi.org/10.1177/2050313X231204193 |
| spellingShingle | Daniel Toshkov Ivanov Nina Stoyanova Yancheva Trifon Kostadinov Valkov Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report SAGE Open Medical Case Reports |
| title | Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report |
| title_full | Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report |
| title_fullStr | Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report |
| title_full_unstemmed | Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report |
| title_short | Clinical presentation of monkeypox in patients with different HIV serostatus – two cases from Bulgaria: A case report |
| title_sort | clinical presentation of monkeypox in patients with different hiv serostatus two cases from bulgaria a case report |
| url | https://doi.org/10.1177/2050313X231204193 |
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