Medaka factor in the germline alpha (figα) is indispensable for oogenesis but not for gonadal sex differentiation

Medaka factor in the germline alpha (figα) is indispensable for oogenesis but not for gonadal sex differentiation

A basic helix-loop-helix transcription factor, figα, is one of the earliest marker genes of oocyte differentiation in vertebrates. In the present study, we made figα knockout medaka by CRISPR/Cas9, expecting aborted progress of oogenesis, to see if differentiation of somatic ovarian tissues is affec...

Full description

Bibliographic Details
Main Authors: Katsuyasu Kamimura, Masato Kinoshita, Akira Kanamori
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-05-01
Series:Aquaculture and Fisheries
Subjects:
bHLH transcription factor
CRISPR/Cas9
Pachytene checkpoint
Oocyte growth
Medaka
Online Access:http://www.sciencedirect.com/science/article/pii/S2468550X2300028X

Similar Items

Similar Items