Repeated Administration of Bone Marrow-Derived Cells Prevents Disease Progression in Experimental Silicosis

Repeated Administration of Bone Marrow-Derived Cells Prevents Disease Progression in Experimental Silicosis

Background/Aims: Bone marrow-derived cells (BMDCs) reduced mechanical and histologic changes in the lung in a murine model of silicosis, but these beneficial effects did not persist in the course of lung injury. We hypothesized that repeated administration of BMDCs may decrease lung inflammation and...

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Bibliographic Details
Main Authors: Miquéias Lopes-Pacheco, Debora G. Xisto, Felipe M. Ornellas, Mariana A. Antunes, Soraia C. Abreu, Patricia R.M. Rocco, Christina M. Takiya, Marcelo M. Morales
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cell therapy
Inflammation
Fibrosis
Elastic fiber
Silicosis
Online Access:http://www.karger.com/Article/FullText/356603

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