Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies
Chronic kidney disease (CKD) affects about 10% of the world’s population. Hyperkalemia is a life-threatening complication in patients with CKD, as it is associated with adverse cardiovascular and kidney outcomes. There are still many challenges and questions to address to improve the currently avail...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/2/353 |
| _version_ | 1827756600133156864 |
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| author | Ruixue Tian Rongshan Li Xiaoshuang Zhou |
| author_facet | Ruixue Tian Rongshan Li Xiaoshuang Zhou |
| author_sort | Ruixue Tian |
| collection | DOAJ |
| description | Chronic kidney disease (CKD) affects about 10% of the world’s population. Hyperkalemia is a life-threatening complication in patients with CKD, as it is associated with adverse cardiovascular and kidney outcomes. There are still many challenges and questions to address to improve the currently available therapeutic strategies to treat hyperkalemia, such as how to approach the emergency management of hyperkalemia. In recent years, in addition to novel oral potassium binders, great progress has been made in the application of novel kidney protective strategies, such as mineralocorticoid receptor antagonists and sodium–glucose cotransporter 2 inhibitors (SGLT2i) in hyperkalemia therapy. This review will discuss the recent advances from clinical trials in the effective management of hyperkalemia in non-dialysis CKD patients, enhancing the knowledge of physicians and internists concerning these newer agents and providing a helpful reference for clinical practice. |
| first_indexed | 2024-03-11T08:27:45Z |
| format | Article |
| id | doaj.art-c83d3ce92433428ab4132dafbea46b4d |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T08:27:45Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-c83d3ce92433428ab4132dafbea46b4d2023-11-16T22:00:37ZengMDPI AGMedicina1010-660X1648-91442023-02-0159235310.3390/medicina59020353Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic StrategiesRuixue Tian0Rongshan Li1Xiaoshuang Zhou2The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan 030012, ChinaDepartment of Nephrology, Shanxi Provincial People’s Hospital, The Fifth Clinical Medical College of Shanxi Medical University, Shanxi Kidney Disease Institute, 29 Shuang Ta East Street, Taiyuan 030012, ChinaDepartment of Nephrology, Shanxi Provincial People’s Hospital, The Fifth Clinical Medical College of Shanxi Medical University, Shanxi Kidney Disease Institute, 29 Shuang Ta East Street, Taiyuan 030012, ChinaChronic kidney disease (CKD) affects about 10% of the world’s population. Hyperkalemia is a life-threatening complication in patients with CKD, as it is associated with adverse cardiovascular and kidney outcomes. There are still many challenges and questions to address to improve the currently available therapeutic strategies to treat hyperkalemia, such as how to approach the emergency management of hyperkalemia. In recent years, in addition to novel oral potassium binders, great progress has been made in the application of novel kidney protective strategies, such as mineralocorticoid receptor antagonists and sodium–glucose cotransporter 2 inhibitors (SGLT2i) in hyperkalemia therapy. This review will discuss the recent advances from clinical trials in the effective management of hyperkalemia in non-dialysis CKD patients, enhancing the knowledge of physicians and internists concerning these newer agents and providing a helpful reference for clinical practice.https://www.mdpi.com/1648-9144/59/2/353hyperkalemiachronic kidney diseasepotassium |
| spellingShingle | Ruixue Tian Rongshan Li Xiaoshuang Zhou Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies Medicina hyperkalemia chronic kidney disease potassium |
| title | Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies |
| title_full | Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies |
| title_fullStr | Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies |
| title_full_unstemmed | Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies |
| title_short | Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies |
| title_sort | recent progresses in non dialysis chronic kidney disease patients with hyperkalemia outcomes and therapeutic strategies |
| topic | hyperkalemia chronic kidney disease potassium |
| url | https://www.mdpi.com/1648-9144/59/2/353 |
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