Reconstituting NK Cells After Allogeneic Stem Cell Transplantation Show Impaired Response to the Fungal Pathogen Aspergillus fumigatus

Reconstituting NK Cells After Allogeneic Stem Cell Transplantation Show Impaired Response to the Fungal Pathogen Aspergillus fumigatus

Delayed natural killer (NK) cell reconstitution after allogeneic stem cell transplantation (alloSCT) is associated with a higher risk of developing invasive aspergillosis. The interaction of NK cells with the human pathogen Aspergillus (A.) fumigatus is mediated by the fungal recognition receptor CD...

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Bibliographic Details
Main Authors: Esther Weiss, Jan Schlegel, Ulrich Terpitz, Michael Weber, Jörg Linde, Anna-Lena Schmitt, Kerstin Hünniger, Lothar Marischen, Florian Gamon, Joachim Bauer, Claudia Löffler, Oliver Kurzai, Charles Oliver Morton, Markus Sauer, Hermann Einsele, Juergen Loeffler
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
natural killer cell
Aspergillus fumigatus
stem cell transplantation
corticosteroids
CCL3
CCL4
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02117/full

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