Effect of bladder distension on arginine vasopressin secretion in rats
Abstract Objective Urine production is regulated throughout the night to ensure that it remains within functional bladder capacity. Increasing bladder capacity may thus play an important role in urine production. We investigated arginine vasopressin (AVP) secretion in female rats anesthetized with u...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-02-01
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| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13104-019-4105-7 |
| _version_ | 1818475468211355648 |
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| author | Yosuke Morizawa Kazumasa Torimoto Shunta Hori Daisuke Gotoh Yasushi Nakai Makito Miyake Kiyohide Fujimoto |
| author_facet | Yosuke Morizawa Kazumasa Torimoto Shunta Hori Daisuke Gotoh Yasushi Nakai Makito Miyake Kiyohide Fujimoto |
| author_sort | Yosuke Morizawa |
| collection | DOAJ |
| description | Abstract Objective Urine production is regulated throughout the night to ensure that it remains within functional bladder capacity. Increasing bladder capacity may thus play an important role in urine production. We investigated arginine vasopressin (AVP) secretion in female rats anesthetized with urethane in the daytime and nighttime under distended/empty bladder conditions. Chronological serum AVP was measured by enzyme immunoassay in rats with distended or empty bladders. Results The mean baseline AVP level was significantly higher in the nighttime than in the daytime (17.21 ± 5.29 vs 11.68 ± 3.16 pg/mL, p = 0.0019). However, serum AVP levels did not change with time in the daytime or nighttime, regardless of an empty or distended bladder. We therefore concluded that AVP secretion was unaffected by bladder filling. |
| first_indexed | 2024-12-10T09:12:58Z |
| format | Article |
| id | doaj.art-c83dd1b3d7a64c4db183fd763e983dd2 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-10T09:12:58Z |
| publishDate | 2019-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-c83dd1b3d7a64c4db183fd763e983dd22022-12-22T01:54:57ZengBMCBMC Research Notes1756-05002019-02-011211410.1186/s13104-019-4105-7Effect of bladder distension on arginine vasopressin secretion in ratsYosuke Morizawa0Kazumasa Torimoto1Shunta Hori2Daisuke Gotoh3Yasushi Nakai4Makito Miyake5Kiyohide Fujimoto6Department of Urology, Nara Medical UniversityDepartment of Urology, Nara Medical UniversityDepartment of Urology, Nara Medical UniversityDepartment of Urology, Nara Medical UniversityDepartment of Urology, Nara Medical UniversityDepartment of Urology, Nara Medical UniversityDepartment of Urology, Nara Medical UniversityAbstract Objective Urine production is regulated throughout the night to ensure that it remains within functional bladder capacity. Increasing bladder capacity may thus play an important role in urine production. We investigated arginine vasopressin (AVP) secretion in female rats anesthetized with urethane in the daytime and nighttime under distended/empty bladder conditions. Chronological serum AVP was measured by enzyme immunoassay in rats with distended or empty bladders. Results The mean baseline AVP level was significantly higher in the nighttime than in the daytime (17.21 ± 5.29 vs 11.68 ± 3.16 pg/mL, p = 0.0019). However, serum AVP levels did not change with time in the daytime or nighttime, regardless of an empty or distended bladder. We therefore concluded that AVP secretion was unaffected by bladder filling.http://link.springer.com/article/10.1186/s13104-019-4105-7Bladder distentionAVPRat |
| spellingShingle | Yosuke Morizawa Kazumasa Torimoto Shunta Hori Daisuke Gotoh Yasushi Nakai Makito Miyake Kiyohide Fujimoto Effect of bladder distension on arginine vasopressin secretion in rats BMC Research Notes Bladder distention AVP Rat |
| title | Effect of bladder distension on arginine vasopressin secretion in rats |
| title_full | Effect of bladder distension on arginine vasopressin secretion in rats |
| title_fullStr | Effect of bladder distension on arginine vasopressin secretion in rats |
| title_full_unstemmed | Effect of bladder distension on arginine vasopressin secretion in rats |
| title_short | Effect of bladder distension on arginine vasopressin secretion in rats |
| title_sort | effect of bladder distension on arginine vasopressin secretion in rats |
| topic | Bladder distention AVP Rat |
| url | http://link.springer.com/article/10.1186/s13104-019-4105-7 |
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