Izokibep: Preclinical development and first-in-human study of a novel IL-17A neutralizing Affibody molecule in patients with plaque psoriasis

ABSTRACTPsoriasis, an immune-mediated inflammatory disease, affects nearly 125 million people globally. The interleukin (IL)-17A homodimer is a key driver of psoriasis and other autoimmune diseases, including psoriatic arthritis, axial spondyloarthritis, hidradenitis suppurativa, and uveitis. Treatm...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Susanne Klint, Joachim Feldwisch, Lindvi Gudmundsdotter, Karin Dillner Bergstedt, Elin Gunneriusson, Ingmarie Höidén Guthenberg, Anders Wennborg, Andrew C. Nyborg, Amol P. Kamboj, Paul M. Peloso, David Bejker, Fredrik Y. Frejd
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Taylor & Francis Group 2023-12-01
Sraith:mAbs
Ábhair:
Rochtain ar líne:https://www.tandfonline.com/doi/10.1080/19420862.2023.2209920