Influence of Nivolumab for Intercellular Adhesion Force between a T Cell and a Cancer Cell Evaluated by AFM Force Spectroscopy

Influence of Nivolumab for Intercellular Adhesion Force between a T Cell and a Cancer Cell Evaluated by AFM Force Spectroscopy

The influence of nivolumab on intercellular adhesion forces between T cells and cancer cells was evaluated quantitatively using atomic force microscopy (AFM). Two model T cells, one expressing high levels of programmed cell death protein 1 (PD-1) (PD-1<sup>high</sup> Jurkat) and the othe...

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Bibliographic Details
Main Authors: Hyonchol Kim, Kenta Ishibashi, Masumi Iijima, Shun’ichi Kuroda, Chikashi Nakamura
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Sensors
Subjects:
atomic force microscopy
nivolumab
PD-1
PD-L1
cell adhesion
microcup
Online Access:https://www.mdpi.com/1424-8220/20/19/5723

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