The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study
<em>Background and Objectives:<b> </b></em>Rheumatoid arthritis (RA) is a severe autoimmune disease characterized by chronic inflammation of the joints accompanied by the progressive deformation and destruction of cartilage and joint bones. This study aims to gain insight int...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1010-660X/56/4/178 |
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| author | Turcu-Stiolica Adina Subtirelu Mihaela-Simona Ciurea Paulina Lucia Dinescu Stefan Cristian Bogdan Maria Barbulescu Andreea Lili Glavan Daniela-Gabriela Turcu-Stiolica Razvan-Aurelian Firulescu Sineta Cristina Chisalau Beatrice Andreea Parvanescu Cristina Dorina Stanoiu Bogdan-Petre Meca Andreea Daniela Neamtu Johny Vreju Florentin-Ananu |
| author_facet | Turcu-Stiolica Adina Subtirelu Mihaela-Simona Ciurea Paulina Lucia Dinescu Stefan Cristian Bogdan Maria Barbulescu Andreea Lili Glavan Daniela-Gabriela Turcu-Stiolica Razvan-Aurelian Firulescu Sineta Cristina Chisalau Beatrice Andreea Parvanescu Cristina Dorina Stanoiu Bogdan-Petre Meca Andreea Daniela Neamtu Johny Vreju Florentin-Ananu |
| author_sort | Turcu-Stiolica Adina |
| collection | DOAJ |
| description | <em>Background and Objectives:<b> </b></em>Rheumatoid arthritis (RA) is a severe autoimmune disease characterized by chronic inflammation of the joints accompanied by the progressive deformation and destruction of cartilage and joint bones. This study aims to gain insight into the outcomes related to adherence in patients with rheumatoid arthritis. Predicting the medication adherence in RA patients is a key point to improve the treatment outcome. <i>Materials and Methods</i>: A number of 119 Romanian patients with RA were included and divided into two groups: first group included 79 patients treated with conventional therapy and second group included 40 patients treated with biologic therapy. A CQR-9 (compliance questionnaire rheumatology with nine items) and PDSQ (psychiatric diagnostic screening questionnaire) were performed to assess correlations between medication adherence, patient sociodemographic variables, 11 psychiatric scales (major depressive disorder, posttraumatic stress disorder, obsessive-compulsive disorder, panic disorder, psychosis, agoraphobia, social phobia, drug abuse/dependence, generalized anxiety disorder, somatization disorder, hypochondriasis) and lifestyle (bulimia, alcohol intake). <i>Results</i>: Whilst modelling factors associated with adherence, it was found that women and patients with higher education are more adherent. From the psychiatric indicators, only major depressive disorder and post-traumatic stress disorder were found to be positively correlated with therapeutic adherence. None of the assessed lifestyle factors influenced the adherence of RA patients. <i>Conclusion</i>: The knowledge of factors that impact on treatment adherence can be useful for clinicians to guide patient-centred care. |
| first_indexed | 2024-03-12T08:46:10Z |
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| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T08:46:10Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-c8450f817541435db5a5e1c2b8d9d8962023-09-02T16:27:09ZengMDPI AGMedicina1010-660X2020-04-015617817810.3390/medicina56040178The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional StudyTurcu-Stiolica Adina0Subtirelu Mihaela-Simona1Ciurea Paulina Lucia2Dinescu Stefan Cristian3Bogdan Maria4Barbulescu Andreea Lili5Glavan Daniela-Gabriela6Turcu-Stiolica Razvan-Aurelian7Firulescu Sineta Cristina8Chisalau Beatrice Andreea9Parvanescu Cristina Dorina10Stanoiu Bogdan-Petre11Meca Andreea Daniela12Neamtu Johny13Vreju Florentin-Ananu14Department of Pharmacoeconomics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Pharmacoeconomics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Rheumatology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Rheumatology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Pharmacology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Pharmacology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Psychiatry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaTrueman Consulting, 200528 Craiova, RomaniaDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Cell and Molecular Biology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Pharmacology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Pharmacy I, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Rheumatology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania<em>Background and Objectives:<b> </b></em>Rheumatoid arthritis (RA) is a severe autoimmune disease characterized by chronic inflammation of the joints accompanied by the progressive deformation and destruction of cartilage and joint bones. This study aims to gain insight into the outcomes related to adherence in patients with rheumatoid arthritis. Predicting the medication adherence in RA patients is a key point to improve the treatment outcome. <i>Materials and Methods</i>: A number of 119 Romanian patients with RA were included and divided into two groups: first group included 79 patients treated with conventional therapy and second group included 40 patients treated with biologic therapy. A CQR-9 (compliance questionnaire rheumatology with nine items) and PDSQ (psychiatric diagnostic screening questionnaire) were performed to assess correlations between medication adherence, patient sociodemographic variables, 11 psychiatric scales (major depressive disorder, posttraumatic stress disorder, obsessive-compulsive disorder, panic disorder, psychosis, agoraphobia, social phobia, drug abuse/dependence, generalized anxiety disorder, somatization disorder, hypochondriasis) and lifestyle (bulimia, alcohol intake). <i>Results</i>: Whilst modelling factors associated with adherence, it was found that women and patients with higher education are more adherent. From the psychiatric indicators, only major depressive disorder and post-traumatic stress disorder were found to be positively correlated with therapeutic adherence. None of the assessed lifestyle factors influenced the adherence of RA patients. <i>Conclusion</i>: The knowledge of factors that impact on treatment adherence can be useful for clinicians to guide patient-centred care.https://www.mdpi.com/1010-660X/56/4/178lifestylesocio-demographic factorsrheumatoid arthritistreatment adherenceCQR-9PDSQ |
| spellingShingle | Turcu-Stiolica Adina Subtirelu Mihaela-Simona Ciurea Paulina Lucia Dinescu Stefan Cristian Bogdan Maria Barbulescu Andreea Lili Glavan Daniela-Gabriela Turcu-Stiolica Razvan-Aurelian Firulescu Sineta Cristina Chisalau Beatrice Andreea Parvanescu Cristina Dorina Stanoiu Bogdan-Petre Meca Andreea Daniela Neamtu Johny Vreju Florentin-Ananu The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study Medicina lifestyle socio-demographic factors rheumatoid arthritis treatment adherence CQR-9 PDSQ |
| title | The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
| title_full | The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
| title_fullStr | The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
| title_full_unstemmed | The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
| title_short | The Influence of Socio-Demographic Factors, Lifestyle and Psychiatric Indicators on Adherence to Treatment of Patients with Rheumatoid Arthritis: A Cross-Sectional Study |
| title_sort | influence of socio demographic factors lifestyle and psychiatric indicators on adherence to treatment of patients with rheumatoid arthritis a cross sectional study |
| topic | lifestyle socio-demographic factors rheumatoid arthritis treatment adherence CQR-9 PDSQ |
| url | https://www.mdpi.com/1010-660X/56/4/178 |
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