Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis.
Hypertension and diabetes comorbidity can increase healthcare expenditure and the risk of coronary heart disease. We conducted a systematic review and meta-analysis to estimate the prevalence of hypertension among people with diabetes in African countries. We searched EMBASE, PubMed and HINARI datab...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-01-01
|
| Series: | PLOS Global Public Health |
| Online Access: | https://doi.org/10.1371/journal.pgph.0001931 |
| _version_ | 1797392892651634688 |
|---|---|
| author | Thomas Hinneh Samuel Akyirem Irene Fosuhemaa Bossman Victor Lambongang Patriot Ofori-Aning Oluwabunmi Ogungbe Yvonne Commodore Mensah |
| author_facet | Thomas Hinneh Samuel Akyirem Irene Fosuhemaa Bossman Victor Lambongang Patriot Ofori-Aning Oluwabunmi Ogungbe Yvonne Commodore Mensah |
| author_sort | Thomas Hinneh |
| collection | DOAJ |
| description | Hypertension and diabetes comorbidity can increase healthcare expenditure and the risk of coronary heart disease. We conducted a systematic review and meta-analysis to estimate the prevalence of hypertension among people with diabetes in African countries. We searched EMBASE, PubMed and HINARI databases from inception to March 2023. Cross-sectional studies reporting the prevalence of hypertension among people with diabetes and published in English in Africa were eligible for inclusion. The cross-sectional study design component of the mixed method appraisal tool was used to assess the quality of the included studies. We quantified the overall and regional prevalence of hypertension among people with diabetes using random-effects meta-analysis. We assessed heterogeneity and publication bias using I2 statistics and funnel plots. Out of 3815 articles retrieved from the various databases, 41 met the inclusion criteria with sample sizes ranging from 80 to 116726. The mean age was 58 years (± 11) and 56% were women. The pooled prevalence of hypertension in people diagnosed with diabetes was 58.1% [95% CI: 52.0% - 63.2%]. By region, Central Africa had the highest hypertension prevalence; 77.6% [95% CI: 53.0% - 91.4%], Southern Africa 69.1% [95% CI: 59.8% - 77.1%;], North Africa 63.4% [95% CI: 37.1% - 69.1%;], West Africa 51.5% [95% CI: 41.8% - 61.1%] and East Africa 53.0% [95% CI: 45.8% - 59.1%]. Increasing age, being overweight/obese, being employed, longer duration of diabetes, urban residence, and male sex were reported to be associated with a higher likelihood of developing hypertension. The high prevalence of hypertension among people with diabetes in Africa highlights the critical need for an integrated differentiated service delivery to improve and strengthen primary care and prevent cardiovascular disease. Findings from this meta-analysis may inform the delivery of interventions to prevent premature cardiovascular disease deaths among persons in the region. |
| first_indexed | 2024-03-08T23:55:06Z |
| format | Article |
| id | doaj.art-c847b3ad221a4ff8bb9e8dc8960661a2 |
| institution | Directory Open Access Journal |
| issn | 2767-3375 |
| language | English |
| last_indexed | 2024-03-08T23:55:06Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLOS Global Public Health |
| spelling | doaj.art-c847b3ad221a4ff8bb9e8dc8960661a22023-12-13T05:57:22ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752023-01-01312e000193110.1371/journal.pgph.0001931Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis.Thomas HinnehSamuel AkyiremIrene Fosuhemaa BossmanVictor LambongangPatriot Ofori-AningOluwabunmi OgungbeYvonne Commodore MensahHypertension and diabetes comorbidity can increase healthcare expenditure and the risk of coronary heart disease. We conducted a systematic review and meta-analysis to estimate the prevalence of hypertension among people with diabetes in African countries. We searched EMBASE, PubMed and HINARI databases from inception to March 2023. Cross-sectional studies reporting the prevalence of hypertension among people with diabetes and published in English in Africa were eligible for inclusion. The cross-sectional study design component of the mixed method appraisal tool was used to assess the quality of the included studies. We quantified the overall and regional prevalence of hypertension among people with diabetes using random-effects meta-analysis. We assessed heterogeneity and publication bias using I2 statistics and funnel plots. Out of 3815 articles retrieved from the various databases, 41 met the inclusion criteria with sample sizes ranging from 80 to 116726. The mean age was 58 years (± 11) and 56% were women. The pooled prevalence of hypertension in people diagnosed with diabetes was 58.1% [95% CI: 52.0% - 63.2%]. By region, Central Africa had the highest hypertension prevalence; 77.6% [95% CI: 53.0% - 91.4%], Southern Africa 69.1% [95% CI: 59.8% - 77.1%;], North Africa 63.4% [95% CI: 37.1% - 69.1%;], West Africa 51.5% [95% CI: 41.8% - 61.1%] and East Africa 53.0% [95% CI: 45.8% - 59.1%]. Increasing age, being overweight/obese, being employed, longer duration of diabetes, urban residence, and male sex were reported to be associated with a higher likelihood of developing hypertension. The high prevalence of hypertension among people with diabetes in Africa highlights the critical need for an integrated differentiated service delivery to improve and strengthen primary care and prevent cardiovascular disease. Findings from this meta-analysis may inform the delivery of interventions to prevent premature cardiovascular disease deaths among persons in the region.https://doi.org/10.1371/journal.pgph.0001931 |
| spellingShingle | Thomas Hinneh Samuel Akyirem Irene Fosuhemaa Bossman Victor Lambongang Patriot Ofori-Aning Oluwabunmi Ogungbe Yvonne Commodore Mensah Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis. PLOS Global Public Health |
| title | Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis. |
| title_full | Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis. |
| title_fullStr | Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis. |
| title_full_unstemmed | Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis. |
| title_short | Regional prevalence of hypertension among people diagnosed with diabetes in Africa, a systematic review and meta-analysis. |
| title_sort | regional prevalence of hypertension among people diagnosed with diabetes in africa a systematic review and meta analysis |
| url | https://doi.org/10.1371/journal.pgph.0001931 |
| work_keys_str_mv | AT thomashinneh regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis AT samuelakyirem regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis AT irenefosuhemaabossman regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis AT victorlambongang regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis AT patriotoforianing regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis AT oluwabunmiogungbe regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis AT yvonnecommodoremensah regionalprevalenceofhypertensionamongpeoplediagnosedwithdiabetesinafricaasystematicreviewandmetaanalysis |