Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis

In recent years, various devices have been approved for peripheral artery disease with femoropopliteal lesions. However, treatment of long, calcified, and diffused lesions is still challenging because these lesions are associated with restenosis. This report described the case of an 82-year-old man...

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Main Authors: Naoki Yoshioka, Kensuke Takagi, Takahiro Tokuda, Yasuhiro Morita, Itsuro Morishima
Format: Article
Language:English
Published: SAGE Publishing 2021-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X211025929
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author Naoki Yoshioka
Kensuke Takagi
Takahiro Tokuda
Yasuhiro Morita
Itsuro Morishima
author_facet Naoki Yoshioka
Kensuke Takagi
Takahiro Tokuda
Yasuhiro Morita
Itsuro Morishima
author_sort Naoki Yoshioka
collection DOAJ
description In recent years, various devices have been approved for peripheral artery disease with femoropopliteal lesions. However, treatment of long, calcified, and diffused lesions is still challenging because these lesions are associated with restenosis. This report described the case of an 82-year-old man with bilateral severely calcified and diffused long lesions in the superficial femoral artery that was treated using polymer-coated paclitaxel-eluting stent and interwoven nitinol stent. After 6 months, in-stent restenosis was observed at the implantation site of the interwoven nitinol stents. Polymer-coated paclitaxel-eluting stents were deployed at the in-stent restenosis site. After another 6 months, angiography and intravascular ultrasound imaging revealed no restenosis at the polymer-coated paclitaxel-eluting stent site. Optical coherence tomography was also performed, revealing that the stent struts were well covered by neointima, which was very thin at approximately 0.1 mm. This representative case demonstrated substantial differences in the effects of devices; in other words, the superiority of polymer-coated paclitaxel-eluting stent in treating long, diffuse, and calcified lesions indicated that its implantation is a reasonable option when the initial gain was obtained following sufficient vessel preparation.
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spelling doaj.art-c8494eda462f49919e725bd12af3b7ac2022-12-21T20:25:27ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2021-06-01910.1177/2050313X211025929Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysisNaoki Yoshioka0Kensuke Takagi1Takahiro Tokuda2Yasuhiro Morita3Itsuro Morishima4Department of Cardiology, Ogaki Municipal Hospital, Ogaki, JapanDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, JapanDepartment of Cardiology, Nagoya Heart Center, Nagoya, JapanDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, JapanDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, JapanIn recent years, various devices have been approved for peripheral artery disease with femoropopliteal lesions. However, treatment of long, calcified, and diffused lesions is still challenging because these lesions are associated with restenosis. This report described the case of an 82-year-old man with bilateral severely calcified and diffused long lesions in the superficial femoral artery that was treated using polymer-coated paclitaxel-eluting stent and interwoven nitinol stent. After 6 months, in-stent restenosis was observed at the implantation site of the interwoven nitinol stents. Polymer-coated paclitaxel-eluting stents were deployed at the in-stent restenosis site. After another 6 months, angiography and intravascular ultrasound imaging revealed no restenosis at the polymer-coated paclitaxel-eluting stent site. Optical coherence tomography was also performed, revealing that the stent struts were well covered by neointima, which was very thin at approximately 0.1 mm. This representative case demonstrated substantial differences in the effects of devices; in other words, the superiority of polymer-coated paclitaxel-eluting stent in treating long, diffuse, and calcified lesions indicated that its implantation is a reasonable option when the initial gain was obtained following sufficient vessel preparation.https://doi.org/10.1177/2050313X211025929
spellingShingle Naoki Yoshioka
Kensuke Takagi
Takahiro Tokuda
Yasuhiro Morita
Itsuro Morishima
Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis
SAGE Open Medical Case Reports
title Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis
title_full Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis
title_fullStr Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis
title_full_unstemmed Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis
title_short Clinical performance of polymer-coated paclitaxel-eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions: Insights from a patient on hemodialysis
title_sort clinical performance of polymer coated paclitaxel eluting stent implanted for diffuse and calcified superficial femoral artery stenotic lesions insights from a patient on hemodialysis
url https://doi.org/10.1177/2050313X211025929
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