An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything

Primary lung lymphoma (PLL) is a rare type of lymphoma confined to the lung at the time of diagnosis. Pulmonary diffuse large B cells lymphoma (P-DLBCL) is the second most common type of PLL and it usually appears radiologically as solitary or multiple nodules or areas of consolidation. We present t...

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Main Authors: Anna Stainer, Paola Faverio, Francesca Bono, Alberto Pesci
Format: Article
Language:English
Published: PAGEPress Publications 2018-05-01
Series:Monaldi Archives for Chest Disease
Subjects:
Online Access:https://www.monaldi-archives.org/index.php/macd/article/view/907
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author Anna Stainer
Paola Faverio
Francesca Bono
Alberto Pesci
author_facet Anna Stainer
Paola Faverio
Francesca Bono
Alberto Pesci
author_sort Anna Stainer
collection DOAJ
description Primary lung lymphoma (PLL) is a rare type of lymphoma confined to the lung at the time of diagnosis. Pulmonary diffuse large B cells lymphoma (P-DLBCL) is the second most common type of PLL and it usually appears radiologically as solitary or multiple nodules or areas of consolidation. We present the case of a 63-year-old Caucasian male who developed severe acute respiratory failure and diffuse ground glass opacities (GGO) on chest computerized tomography. Diffuse GGO may be the radiological expression of very different diseases, ranging from infectious processes to interstitial lung diseases (ILDs) and neoplastic diseases. In our case, pneumonia and de novo ILD were initially considered given the symptoms and past medical history. However, bronchoscopy with trans-bronchial biopsies demonstrated the presence of P-DLBCL, despite an unusual radiological presentation and negative cytological analyses on bronchoalveolar lavage. In conclusion, P-DLBCL should be considered among the many differential diagnoses of diffuse GGO.
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spelling doaj.art-c8498a2c03a14b1fb419a548f00801232022-12-22T03:25:25ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642018-05-0188110.4081/monaldi.2018.907An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anythingAnna Stainer0Paola Faverio1Francesca Bono2Alberto Pesci3University of Milan Bicocca, San Gerardo Hospital, Respiratory UnitUniversity of Milan Bicocca, San Gerardo Hospital, Respiratory UnitUniversity of Milan Bicocca, Department of Medicine and SurgeryUniversity of Milan Bicocca, San Gerardo Hospital, Respiratory UnitPrimary lung lymphoma (PLL) is a rare type of lymphoma confined to the lung at the time of diagnosis. Pulmonary diffuse large B cells lymphoma (P-DLBCL) is the second most common type of PLL and it usually appears radiologically as solitary or multiple nodules or areas of consolidation. We present the case of a 63-year-old Caucasian male who developed severe acute respiratory failure and diffuse ground glass opacities (GGO) on chest computerized tomography. Diffuse GGO may be the radiological expression of very different diseases, ranging from infectious processes to interstitial lung diseases (ILDs) and neoplastic diseases. In our case, pneumonia and de novo ILD were initially considered given the symptoms and past medical history. However, bronchoscopy with trans-bronchial biopsies demonstrated the presence of P-DLBCL, despite an unusual radiological presentation and negative cytological analyses on bronchoalveolar lavage. In conclusion, P-DLBCL should be considered among the many differential diagnoses of diffuse GGO.https://www.monaldi-archives.org/index.php/macd/article/view/907Pulmonary lymphomaground glass opacitiesinterstitial lung disease.
spellingShingle Anna Stainer
Paola Faverio
Francesca Bono
Alberto Pesci
An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything
Monaldi Archives for Chest Disease
Pulmonary lymphoma
ground glass opacities
interstitial lung disease.
title An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything
title_full An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything
title_fullStr An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything
title_full_unstemmed An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything
title_short An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything
title_sort unusual presentation of pulmonary lymphoma when diffuse ground glass opacities can mean anything
topic Pulmonary lymphoma
ground glass opacities
interstitial lung disease.
url https://www.monaldi-archives.org/index.php/macd/article/view/907
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