Tanshinone IIA Has a Potential Therapeutic Effect on Kawasaki Disease and Suppresses Megakaryocytes in Rabbits With Immune Vasculitis

Tanshinone IIA Has a Potential Therapeutic Effect on Kawasaki Disease and Suppresses Megakaryocytes in Rabbits With Immune Vasculitis

Background and ObjectiveIt is urgent to find out an alternative therapy for Kawasaki disease (KD) since around 20% patients are resistant to intravenous immunoglobulin (IVIG) or aspirin. Tanshinone IIA is the active component of the traditional Chinese medicine Danshen (Salvia miltiorrhiza), which h...

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Bibliographic Details
Main Authors: Hui Chen, Huiying Shu, Weiqing Su, Bo Li, Hua Zhang, Liang Li, Chao Lin, Wenfang Yi, Xiao-Yong Zhan, Chun Chen, Xiaojing Li, Yanqi Yang, Min Zhou, Mo Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
tanshinone IIA
Kawasaki disease
immune vasculitis
megakaryocyte
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.873851/full

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