A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples
The proper handling of samples to be analyzed by mass spectrometry (MS) can guarantee excellent results and a greater depth of analysis when working in quantitative proteomics. This is critical when trying to assess non-traditional sources such as ear wax, saliva, vitreous humor, aqueous humor, tear...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-10-01
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| Series: | Proteomes |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2227-7382/4/4/31 |
| _version_ | 1817992320439549952 |
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| author | Rígel Licier Eric Miranda Horacio Serrano |
| author_facet | Rígel Licier Eric Miranda Horacio Serrano |
| author_sort | Rígel Licier |
| collection | DOAJ |
| description | The proper handling of samples to be analyzed by mass spectrometry (MS) can guarantee excellent results and a greater depth of analysis when working in quantitative proteomics. This is critical when trying to assess non-traditional sources such as ear wax, saliva, vitreous humor, aqueous humor, tears, nipple aspirate fluid, breast milk/colostrum, cervical-vaginal fluid, nasal secretions, bronco-alveolar lavage fluid, and stools. We intend to provide the investigator with relevant aspects of quantitative proteomics and to recognize the most recent clinical research work conducted with atypical samples and analyzed by quantitative proteomics. Having as reference the most recent and different approaches used with non-traditional sources allows us to compare new strategies in the development of novel experimental models. On the other hand, these references help us to contribute significantly to the understanding of the proportions of proteins in different proteomes of clinical interest and may lead to potential advances in the emerging field of precision medicine. |
| first_indexed | 2024-04-14T01:24:48Z |
| format | Article |
| id | doaj.art-c84c2ab46975447ebe11f8154afd5fe3 |
| institution | Directory Open Access Journal |
| issn | 2227-7382 |
| language | English |
| last_indexed | 2024-04-14T01:24:48Z |
| publishDate | 2016-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Proteomes |
| spelling | doaj.art-c84c2ab46975447ebe11f8154afd5fe32022-12-22T02:20:31ZengMDPI AGProteomes2227-73822016-10-01443110.3390/proteomes4040031proteomes4040031A Quantitative Proteomics Approach to Clinical Research with Non-Traditional SamplesRígel Licier0Eric Miranda1Horacio Serrano2Department of Medicine, San Juan Bautista School of Medicine, Caguas 00727, Puerto RicoQuantitative Proteomics Laboratory, Comprehensive Cancer Center of Puerto Rico, San Juan 00936, Puerto RicoQuantitative Proteomics Laboratory, Comprehensive Cancer Center of Puerto Rico, San Juan 00936, Puerto RicoThe proper handling of samples to be analyzed by mass spectrometry (MS) can guarantee excellent results and a greater depth of analysis when working in quantitative proteomics. This is critical when trying to assess non-traditional sources such as ear wax, saliva, vitreous humor, aqueous humor, tears, nipple aspirate fluid, breast milk/colostrum, cervical-vaginal fluid, nasal secretions, bronco-alveolar lavage fluid, and stools. We intend to provide the investigator with relevant aspects of quantitative proteomics and to recognize the most recent clinical research work conducted with atypical samples and analyzed by quantitative proteomics. Having as reference the most recent and different approaches used with non-traditional sources allows us to compare new strategies in the development of novel experimental models. On the other hand, these references help us to contribute significantly to the understanding of the proportions of proteins in different proteomes of clinical interest and may lead to potential advances in the emerging field of precision medicine.http://www.mdpi.com/2227-7382/4/4/31quantitative proteomicsMS/MSclinical samplesprecision medicinescreening |
| spellingShingle | Rígel Licier Eric Miranda Horacio Serrano A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples Proteomes quantitative proteomics MS/MS clinical samples precision medicine screening |
| title | A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples |
| title_full | A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples |
| title_fullStr | A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples |
| title_full_unstemmed | A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples |
| title_short | A Quantitative Proteomics Approach to Clinical Research with Non-Traditional Samples |
| title_sort | quantitative proteomics approach to clinical research with non traditional samples |
| topic | quantitative proteomics MS/MS clinical samples precision medicine screening |
| url | http://www.mdpi.com/2227-7382/4/4/31 |
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