Biomarkers, Clinical Features, and Rechallenge for Immune Checkpoint Inhibitor Renal Immune-Related Adverse Events

Biomarkers, Clinical Features, and Rechallenge for Immune Checkpoint Inhibitor Renal Immune-Related Adverse Events

Introduction: Immune checkpoint inhibitors (ICIs) are effective in treating several cancers; however, acute kidney injury (AKI) can occur as part as an immune-related adverse event (iRAE). Biomarkers at the time of AKI diagnosis may help determine whether they are ICI- related and guide therapeutic...

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Bibliographic Details
Main Authors: Busra Isik, Mariam P. Alexander, Sandhya Manohar, Lisa Vaughan, Lisa Kottschade, Svetomir Markovic, John Lieske, Aleksandra Kukla, Nelson Leung, Sandra M. Herrmann
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Kidney International Reports
Subjects:
acute kidney injury
biomarkers
immune checkpoint inhibitors
immune checkpoint-rechatllenge
immune-related adverse event
interstitial nephritis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024921000152

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