Schistosoma mansoni Fibroblast Growth Factor Receptor A Orchestrates Multiple Functions in Schistosome Biology and in the Host-Parasite Interplay

Schistosoma mansoni Fibroblast Growth Factor Receptor A Orchestrates Multiple Functions in Schistosome Biology and in the Host-Parasite Interplay

Stem cells play significant roles in driving the complex life cycle of Schistosoma mansoni. Fibroblast growth factor (FGF) receptor A (SmFGFRA) is essential for maintaining the integrity of schistosome stem cells. Using immunolocalization, we demonstrated that SmFGFRA was distributed abundantly in g...

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Bibliographic Details
Main Authors: Xiaofeng Du, Donald P. McManus, Conor E. Fogarty, Malcolm K. Jones, Hong You
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Schistosoma mansoni
fibroblast growth factor receptor A
stem cell marker
immunolocalization
host-parasite interplay
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.868077/full

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