Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database
Abstract Objective: To characterize the causes of mortality in patients with systemic lupus erythematosus (SLE) in Brazil between 2002 and 2011. Methods: An exploratory ecological study of a time series using data from the Mortality Information System of DATASUS, the Department of the Unified Heal...
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Sociedade Brasileira de Reumatologia
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| Series: | Revista Brasileira de Reumatologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042017000600574&lng=en&tlng=en |
| _version_ | 1819122485236334592 |
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| author | Luisa Ribeiro Costi Hatsumi Miyashiro Iwamoto Dilma Costa de Oliveira Neves Cezar Augusto Muniz Caldas |
| author_facet | Luisa Ribeiro Costi Hatsumi Miyashiro Iwamoto Dilma Costa de Oliveira Neves Cezar Augusto Muniz Caldas |
| author_sort | Luisa Ribeiro Costi |
| collection | DOAJ |
| description | Abstract Objective: To characterize the causes of mortality in patients with systemic lupus erythematosus (SLE) in Brazil between 2002 and 2011. Methods: An exploratory ecological study of a time series using data from the Mortality Information System of DATASUS, the Department of the Unified Health System (Brazil's National Health System). Results: Brazil's SLE mortality rate was 4.76 deaths/105 inhabitants. The mortality rate was higher in the Midwest, North and Southeast regions than in the country as a whole. There were 6.3% fewer and 4.2% more deaths than expected in the Northeast and Southeast regions, respectively. The mean age at death was 40.7 ± 18 years, and 45.61% of deaths occurred between the ages of 20 and 39. Incidence was highest in women (90.7%) and whites (49.2%). Disorders of the musculoskeletal system and connective tissue were mentioned as an underlying cause of death in 77.5% of cases, and diseases of the circulatory system and infectious and parasitic diseases were also noted in fewer cases. SLE was mentioned as an underlying cause of death in 77% of cases, with no difference between the Brazilian regions (p = 0.2058). The main SLE-related causes of death were, sequentially, diseases of the respiratory and circulatory systems and infectious and parasitic diseases. Conclusions: This study identified a need for greater control of risk factors for cardiovascular diseases and a better understanding of the pathogenesis of atherosclerosis in SLE. Infectious causes are still frequent, and management should be improved, especially in the early stages of the disease. |
| first_indexed | 2024-12-22T06:53:12Z |
| format | Article |
| id | doaj.art-c8550ec1c4a841b9b908f04dc1e48c41 |
| institution | Directory Open Access Journal |
| issn | 1809-4570 |
| language | English |
| last_indexed | 2024-12-22T06:53:12Z |
| publisher | Sociedade Brasileira de Reumatologia |
| record_format | Article |
| series | Revista Brasileira de Reumatologia |
| spelling | doaj.art-c8550ec1c4a841b9b908f04dc1e48c412022-12-21T18:35:04ZengSociedade Brasileira de ReumatologiaRevista Brasileira de Reumatologia1809-457057657458210.1016/j.rbre.2017.09.001S0482-50042017000600574Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health databaseLuisa Ribeiro CostiHatsumi Miyashiro IwamotoDilma Costa de Oliveira NevesCezar Augusto Muniz CaldasAbstract Objective: To characterize the causes of mortality in patients with systemic lupus erythematosus (SLE) in Brazil between 2002 and 2011. Methods: An exploratory ecological study of a time series using data from the Mortality Information System of DATASUS, the Department of the Unified Health System (Brazil's National Health System). Results: Brazil's SLE mortality rate was 4.76 deaths/105 inhabitants. The mortality rate was higher in the Midwest, North and Southeast regions than in the country as a whole. There were 6.3% fewer and 4.2% more deaths than expected in the Northeast and Southeast regions, respectively. The mean age at death was 40.7 ± 18 years, and 45.61% of deaths occurred between the ages of 20 and 39. Incidence was highest in women (90.7%) and whites (49.2%). Disorders of the musculoskeletal system and connective tissue were mentioned as an underlying cause of death in 77.5% of cases, and diseases of the circulatory system and infectious and parasitic diseases were also noted in fewer cases. SLE was mentioned as an underlying cause of death in 77% of cases, with no difference between the Brazilian regions (p = 0.2058). The main SLE-related causes of death were, sequentially, diseases of the respiratory and circulatory systems and infectious and parasitic diseases. Conclusions: This study identified a need for greater control of risk factors for cardiovascular diseases and a better understanding of the pathogenesis of atherosclerosis in SLE. Infectious causes are still frequent, and management should be improved, especially in the early stages of the disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042017000600574&lng=en&tlng=enSystemic erythematosus lupusMortalityBrazil |
| spellingShingle | Luisa Ribeiro Costi Hatsumi Miyashiro Iwamoto Dilma Costa de Oliveira Neves Cezar Augusto Muniz Caldas Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database Revista Brasileira de Reumatologia Systemic erythematosus lupus Mortality Brazil |
| title | Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database |
| title_full | Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database |
| title_fullStr | Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database |
| title_full_unstemmed | Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database |
| title_short | Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database |
| title_sort | mortality from systemic erythematosus lupus in brazil evaluation of causes according to the government health database |
| topic | Systemic erythematosus lupus Mortality Brazil |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042017000600574&lng=en&tlng=en |
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