Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection
Interferon-based simeprevir therapy showed high efficacy and tolerability in children with genotype 1 hepatitis C virus infection. While direct-acting antivirals (DAAs) therapy are undergoing study in children, this regimen is considered an available therapeutic option for selected patients in count...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-09-01
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| Series: | Annals of Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119302522 |
| _version_ | 1818671891114622976 |
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| author | Mitsuyoshi Suzuki Kei Minowa Hitoshi Tajiri |
| author_facet | Mitsuyoshi Suzuki Kei Minowa Hitoshi Tajiri |
| author_sort | Mitsuyoshi Suzuki |
| collection | DOAJ |
| description | Interferon-based simeprevir therapy showed high efficacy and tolerability in children with genotype 1 hepatitis C virus infection. While direct-acting antivirals (DAAs) therapy are undergoing study in children, this regimen is considered an available therapeutic option for selected patients in countries where DAAs have not yet been approved. |
| first_indexed | 2024-12-17T07:31:12Z |
| format | Article |
| id | doaj.art-c859fa52d41847428e3bdee86435551f |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-12-17T07:31:12Z |
| publishDate | 2018-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-c859fa52d41847428e3bdee86435551f2022-12-21T21:58:30ZengElsevierAnnals of Hepatology1665-26812018-09-01175756758Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral InfectionMitsuyoshi Suzuki0Kei Minowa1Hitoshi Tajiri2Department of Pediatrics, Juntendo University Faculty of Medicine, Bunkyo-ku, Tokyo, Japan; Correspondence and reprint request:Department of Pediatrics, Juntendo University Faculty of Medicine, Bunkyo-ku, Tokyo, JapanDepartment of Pediatrics, Osaka General Medical Center, Sumiyoshi-ku, Osaka, JapanInterferon-based simeprevir therapy showed high efficacy and tolerability in children with genotype 1 hepatitis C virus infection. While direct-acting antivirals (DAAs) therapy are undergoing study in children, this regimen is considered an available therapeutic option for selected patients in countries where DAAs have not yet been approved.http://www.sciencedirect.com/science/article/pii/S1665268119302522PeginterferonRibavirinDirect-acting antiviralsHyperbilirubinemiaShorter treatment time |
| spellingShingle | Mitsuyoshi Suzuki Kei Minowa Hitoshi Tajiri Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection Annals of Hepatology Peginterferon Ribavirin Direct-acting antivirals Hyperbilirubinemia Shorter treatment time |
| title | Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection |
| title_full | Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection |
| title_fullStr | Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection |
| title_full_unstemmed | Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection |
| title_short | Interferon-based Simeprevir Therapy for Pediatric Patients with Chronic Hepatitis C Viral Infection |
| title_sort | interferon based simeprevir therapy for pediatric patients with chronic hepatitis c viral infection |
| topic | Peginterferon Ribavirin Direct-acting antivirals Hyperbilirubinemia Shorter treatment time |
| url | http://www.sciencedirect.com/science/article/pii/S1665268119302522 |
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