Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review
Abstract Objective To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. Methods By searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in Decemb...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-07-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | http://link.springer.com/article/10.1186/s13018-018-0836-8 |
| _version_ | 1811264101900353536 |
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| author | Ya-Zhou Zhang Xu-Yang Cao Xi-Cheng Li Jia Chen Yue-Yuan Zhao Zhi Tian Wang Zheng |
| author_facet | Ya-Zhou Zhang Xu-Yang Cao Xi-Cheng Li Jia Chen Yue-Yuan Zhao Zhi Tian Wang Zheng |
| author_sort | Ya-Zhou Zhang |
| collection | DOAJ |
| description | Abstract Objective To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. Methods By searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in December 2017, qualified studies were identified and relevant literature sources were also searched. The qualified studies included prospective cohort studies and cross-sectional studies. Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). Summary receiver operating characteristic (SROC) analyses were performed for meniscal tears. Results Forty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. The global sensitivity and specificity of MRI in early osteonecrosis of the femoral head were 93.0% (95% CI 92.0–94.0%) and 91.0% (95% CI 89.0%–93.0%), respectively. The global positive likelihood ratio and global negative likelihood ratio of MRI in early osteonecrosis of the femoral head were 2.74 (95% CI 1.98–3.79) and 0.18 (95% CI 0.14–0.23), respectively. The global DOR was 27.27 (95% CI 17.02–43.67), and the area under the SROC was 93.38% (95% CI 90.87%–95.89%). Conclusions This review provides a systematic review and meta-analysis to evaluate the diagnostic accuracy of MRI in early osteonecrosis of the femoral head. Moderate to strong evidence indicated that MRI appears to be significantly associated with higher diagnostic accuracy for early osteonecrosis of the femoral head. |
| first_indexed | 2024-04-12T19:57:00Z |
| format | Article |
| id | doaj.art-c85d55b3970f4599bbf85cb906b6b285 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-12T19:57:00Z |
| publishDate | 2018-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-c85d55b3970f4599bbf85cb906b6b2852022-12-22T03:18:38ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2018-07-011311810.1186/s13018-018-0836-8Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic reviewYa-Zhou Zhang0Xu-Yang Cao1Xi-Cheng Li2Jia Chen3Yue-Yuan Zhao4Zhi Tian5Wang Zheng6Department of Orthopedics, Heibei General HospitalDepartment of Orthopedics, Heibei General HospitalDepartment of Orthopedics, Heibei General HospitalDepartment of Orthopedics, Heibei General HospitalDepartment of Orthopedics, Heibei General HospitalDepartment of Orthopedics, Heibei General HospitalDepartment of Orthopedics, Heibei General HospitalAbstract Objective To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. Methods By searching multiple databases and sources, including PubMed, Cochrane, and Embase database, by the index words updated in December 2017, qualified studies were identified and relevant literature sources were also searched. The qualified studies included prospective cohort studies and cross-sectional studies. Heterogeneity of the included studies were reviewed to select proper effect model for pooled weighted sensitivity, specificity, and diagnostic odds ratio (DOR). Summary receiver operating characteristic (SROC) analyses were performed for meniscal tears. Results Forty-three studies related to diagnostic accuracy of MRI to detect early osteonecrosis of the femoral head were involved in the meta-analysis. The global sensitivity and specificity of MRI in early osteonecrosis of the femoral head were 93.0% (95% CI 92.0–94.0%) and 91.0% (95% CI 89.0%–93.0%), respectively. The global positive likelihood ratio and global negative likelihood ratio of MRI in early osteonecrosis of the femoral head were 2.74 (95% CI 1.98–3.79) and 0.18 (95% CI 0.14–0.23), respectively. The global DOR was 27.27 (95% CI 17.02–43.67), and the area under the SROC was 93.38% (95% CI 90.87%–95.89%). Conclusions This review provides a systematic review and meta-analysis to evaluate the diagnostic accuracy of MRI in early osteonecrosis of the femoral head. Moderate to strong evidence indicated that MRI appears to be significantly associated with higher diagnostic accuracy for early osteonecrosis of the femoral head.http://link.springer.com/article/10.1186/s13018-018-0836-8Meta-analysisEarly osteonecrosis of the femoral headMagnetic resonance imagingDiagnostic accuracy |
| spellingShingle | Ya-Zhou Zhang Xu-Yang Cao Xi-Cheng Li Jia Chen Yue-Yuan Zhao Zhi Tian Wang Zheng Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review Journal of Orthopaedic Surgery and Research Meta-analysis Early osteonecrosis of the femoral head Magnetic resonance imaging Diagnostic accuracy |
| title | Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review |
| title_full | Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review |
| title_fullStr | Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review |
| title_full_unstemmed | Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review |
| title_short | Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review |
| title_sort | accuracy of mri diagnosis of early osteonecrosis of the femoral head a meta analysis and systematic review |
| topic | Meta-analysis Early osteonecrosis of the femoral head Magnetic resonance imaging Diagnostic accuracy |
| url | http://link.springer.com/article/10.1186/s13018-018-0836-8 |
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