Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection
Periprosthetic joint infections are devastating complications for patients and for our health system. With growing demand for arthroplasty, the incidence of these infections is projected to increase exponentially. This paper is a review of existing animal models to study periprosthetic infection aim...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/925906 |
| _version_ | 1826998597115183104 |
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| author | Alexandra I. Stavrakis Jared A. Niska Amanda H. Loftin Fabrizio Billi Nicholas M. Bernthal |
| author_facet | Alexandra I. Stavrakis Jared A. Niska Amanda H. Loftin Fabrizio Billi Nicholas M. Bernthal |
| author_sort | Alexandra I. Stavrakis |
| collection | DOAJ |
| description | Periprosthetic joint infections are devastating complications for patients and for our health system. With growing demand for arthroplasty, the incidence of these infections is projected to increase exponentially. This paper is a review of existing animal models to study periprosthetic infection aimed at providing scientists with a succinct presentation of strengths and weaknesses of available in vivo systems. These systems represent the tools available to investigate novel antimicrobial therapies and reduce the clinical and economic impact of implant infections. |
| first_indexed | 2024-04-11T23:09:08Z |
| format | Article |
| id | doaj.art-c866460a21634350be7cdee0803624b7 |
| institution | Directory Open Access Journal |
| issn | 1537-744X |
| language | English |
| last_indexed | 2025-02-18T10:17:47Z |
| publishDate | 2013-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj.art-c866460a21634350be7cdee0803624b72024-11-02T05:32:00ZengHindawi LimitedThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/925906925906Understanding Infection: A Primer on Animal Models of Periprosthetic Joint InfectionAlexandra I. Stavrakis0Jared A. Niska1Amanda H. Loftin2Fabrizio Billi3Nicholas M. Bernthal4Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Center for Health Sciences (CHS), Rm 76-143, Los Angeles, CA 90095, USAOrthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Center for Health Sciences (CHS), Rm 76-143, Los Angeles, CA 90095, USAOrthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Center for Health Sciences (CHS), Rm 76-143, Los Angeles, CA 90095, USAOrthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Center for Health Sciences (CHS), Rm 76-143, Los Angeles, CA 90095, USAOrthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Center for Health Sciences (CHS), Rm 76-143, Los Angeles, CA 90095, USAPeriprosthetic joint infections are devastating complications for patients and for our health system. With growing demand for arthroplasty, the incidence of these infections is projected to increase exponentially. This paper is a review of existing animal models to study periprosthetic infection aimed at providing scientists with a succinct presentation of strengths and weaknesses of available in vivo systems. These systems represent the tools available to investigate novel antimicrobial therapies and reduce the clinical and economic impact of implant infections.http://dx.doi.org/10.1155/2013/925906 |
| spellingShingle | Alexandra I. Stavrakis Jared A. Niska Amanda H. Loftin Fabrizio Billi Nicholas M. Bernthal Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection The Scientific World Journal |
| title | Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection |
| title_full | Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection |
| title_fullStr | Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection |
| title_full_unstemmed | Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection |
| title_short | Understanding Infection: A Primer on Animal Models of Periprosthetic Joint Infection |
| title_sort | understanding infection a primer on animal models of periprosthetic joint infection |
| url | http://dx.doi.org/10.1155/2013/925906 |
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