Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia
Background and Objectives: Burkholderia cepacia is one of the multiple intrinsic resistant bacteria causing opportunistic infections. The study aimed to determine the distribution of B. cepacia isolates based on types of clinical specimen, hospital wards, and the patient's gender-age and to ev...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-02-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/3847 |
| _version_ | 1797902837627224064 |
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| author | Suhartono Suhartono Wilda Mahdani Nyak Naiza Muzayanna |
| author_facet | Suhartono Suhartono Wilda Mahdani Nyak Naiza Muzayanna |
| author_sort | Suhartono Suhartono |
| collection | DOAJ |
| description |
Background and Objectives: Burkholderia cepacia is one of the multiple intrinsic resistant bacteria causing opportunistic infections. The study aimed to determine the distribution of B. cepacia isolates based on types of clinical specimen, hospital wards, and the patient's gender-age and to evaluate their antibiotic susceptibility.
Materials and Methods: This study involved isolating, identifying, and testing antibiotic susceptibility of B. cepacia isolates recovered from clinical specimens of Dr. Zainoel Abidin general hospital (RSUDZA) Banda Aceh Indonesia during March 2019-March 2022.
Results: In total, there were 3,622 Gram-negative bacterial isolates of 10,192 clinical specimens obtained during the study period and B. cepacia was positively detected in 127 isolates (1.24%). Most of the 127 isolates of B. cepacia were found in blood and sterile body fluid samples (55.11%) followed by urine and pus samples accounting for 23.62% and 13.37%, respectively. The internal medicine wards had the highest number of detected B. cepacia isolates at 28.3%. B. cepacia infections were more common in men (59.05%) and people over 45 years old (41.73%). The bacteria were highly sensitive to the antibiotic ceftazidime (92.7%).
Conclusion: Culture examination of clinical specimens is not required for confirmed infections, despite being essential for appropriate antibiotic treatment. Implementing surveillance programs and judicious use of antibiotics can prevent bacterial transmission.
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| first_indexed | 2024-04-10T09:22:29Z |
| format | Article |
| id | doaj.art-c86a8d3b273140d197ffd3237d0efa35 |
| institution | Directory Open Access Journal |
| issn | 2008-3289 2008-4447 |
| language | English |
| last_indexed | 2024-04-10T09:22:29Z |
| publishDate | 2023-02-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj.art-c86a8d3b273140d197ffd3237d0efa352023-02-20T08:49:14ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472023-02-0115110.18502/ijm.v15i1.11916Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, IndonesiaSuhartono Suhartono0Wilda Mahdani1Nyak Naiza Muzayanna2Department of Biology, Faculty of Mathematics and Natural Science, Universitas Syiah Kuala, Banda Aceh, IndonesiaDepartment of Microbiology, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, IndonesiaDepartment of Biology, Faculty of Mathematics and Natural Science, Universitas Syiah Kuala, Banda Aceh, Indonesia Background and Objectives: Burkholderia cepacia is one of the multiple intrinsic resistant bacteria causing opportunistic infections. The study aimed to determine the distribution of B. cepacia isolates based on types of clinical specimen, hospital wards, and the patient's gender-age and to evaluate their antibiotic susceptibility. Materials and Methods: This study involved isolating, identifying, and testing antibiotic susceptibility of B. cepacia isolates recovered from clinical specimens of Dr. Zainoel Abidin general hospital (RSUDZA) Banda Aceh Indonesia during March 2019-March 2022. Results: In total, there were 3,622 Gram-negative bacterial isolates of 10,192 clinical specimens obtained during the study period and B. cepacia was positively detected in 127 isolates (1.24%). Most of the 127 isolates of B. cepacia were found in blood and sterile body fluid samples (55.11%) followed by urine and pus samples accounting for 23.62% and 13.37%, respectively. The internal medicine wards had the highest number of detected B. cepacia isolates at 28.3%. B. cepacia infections were more common in men (59.05%) and people over 45 years old (41.73%). The bacteria were highly sensitive to the antibiotic ceftazidime (92.7%). Conclusion: Culture examination of clinical specimens is not required for confirmed infections, despite being essential for appropriate antibiotic treatment. Implementing surveillance programs and judicious use of antibiotics can prevent bacterial transmission. https://ijm.tums.ac.ir/index.php/ijm/article/view/3847Antimicrobial resistance;Burkholderia cepacia;Prevalence |
| spellingShingle | Suhartono Suhartono Wilda Mahdani Nyak Naiza Muzayanna Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia Iranian Journal of Microbiology Antimicrobial resistance; Burkholderia cepacia; Prevalence |
| title | Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia |
| title_full | Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia |
| title_fullStr | Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia |
| title_full_unstemmed | Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia |
| title_short | Prevalence of Burkholderia cepacia recovered from clinical specimens in the Zainoel Abidin general hospital, Banda Aceh, Indonesia |
| title_sort | prevalence of burkholderia cepacia recovered from clinical specimens in the zainoel abidin general hospital banda aceh indonesia |
| topic | Antimicrobial resistance; Burkholderia cepacia; Prevalence |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/3847 |
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