The optimal choice of an analgesic and antipyretic drug in paediatric practice
Onset of fever and pain syndrome in children is one of the most frequent reasons parents take their children to a paediatrician. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve such symptoms. The mechanism of action of NSAIDs is to inhibit the activity of the enzyme called...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2019-02-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/2862 |
| _version_ | 1797841454557560832 |
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| author | V. N. Drozdov A. A. Bagdasaryan S. Yu. Serebrova K. M. Muratov A. K. Starodubtsev D. A. Bondarenko |
| author_facet | V. N. Drozdov A. A. Bagdasaryan S. Yu. Serebrova K. M. Muratov A. K. Starodubtsev D. A. Bondarenko |
| author_sort | V. N. Drozdov |
| collection | DOAJ |
| description | Onset of fever and pain syndrome in children is one of the most frequent reasons parents take their children to a paediatrician. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve such symptoms. The mechanism of action of NSAIDs is to inhibit the activity of the enzyme called cyclooxygenase (COX). Paracetamol, one of the drugs that inhibit COX, exerts its pharmacodynamic effect in the central nervous system, thereby providing antipyretic and analgesic effects, but it is ineffective in stopping inflammation. Such common conditions in children as fever and pain syndrome of mild to medium intensity are among the indications for use of Efferalgan containing paracetamol as an active ingredient. Solution and rectal suppositories are the most commonly used dosage forms of Efferalgan in children, as these dosage forms can be used, when the child reaches 1 and 3 months of age, respectively. The correct dose of paracetamol for a child depends on their weight. It should be remembered that the relief of a fever or pain syndrome is a symptomatic treatment. Therefore, if they appear, you should visit a doctor to identify carefully the possible cause and select the appropriate therapy. |
| first_indexed | 2024-04-09T16:31:09Z |
| format | Article |
| id | doaj.art-c8745dc265f1445ea82e92ab6b32d46c |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:31:09Z |
| publishDate | 2019-02-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-c8745dc265f1445ea82e92ab6b32d46c2023-04-23T06:57:06ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-02-010210611210.21518/2079-701X-2019-2-106-1122793The optimal choice of an analgesic and antipyretic drug in paediatric practiceV. N. Drozdov0A. A. Bagdasaryan1S. Yu. Serebrova2K. M. Muratov3A. K. Starodubtsev4D. A. Bondarenko5Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University); Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian FederationFederal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)Onset of fever and pain syndrome in children is one of the most frequent reasons parents take their children to a paediatrician. Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve such symptoms. The mechanism of action of NSAIDs is to inhibit the activity of the enzyme called cyclooxygenase (COX). Paracetamol, one of the drugs that inhibit COX, exerts its pharmacodynamic effect in the central nervous system, thereby providing antipyretic and analgesic effects, but it is ineffective in stopping inflammation. Such common conditions in children as fever and pain syndrome of mild to medium intensity are among the indications for use of Efferalgan containing paracetamol as an active ingredient. Solution and rectal suppositories are the most commonly used dosage forms of Efferalgan in children, as these dosage forms can be used, when the child reaches 1 and 3 months of age, respectively. The correct dose of paracetamol for a child depends on their weight. It should be remembered that the relief of a fever or pain syndrome is a symptomatic treatment. Therefore, if they appear, you should visit a doctor to identify carefully the possible cause and select the appropriate therapy.https://www.med-sovet.pro/jour/article/view/2862fever in childrenpain syndrome in childrennonsteroidal anti-inflammatory drugsparacetamol |
| spellingShingle | V. N. Drozdov A. A. Bagdasaryan S. Yu. Serebrova K. M. Muratov A. K. Starodubtsev D. A. Bondarenko The optimal choice of an analgesic and antipyretic drug in paediatric practice Медицинский совет fever in children pain syndrome in children nonsteroidal anti-inflammatory drugs paracetamol |
| title | The optimal choice of an analgesic and antipyretic drug in paediatric practice |
| title_full | The optimal choice of an analgesic and antipyretic drug in paediatric practice |
| title_fullStr | The optimal choice of an analgesic and antipyretic drug in paediatric practice |
| title_full_unstemmed | The optimal choice of an analgesic and antipyretic drug in paediatric practice |
| title_short | The optimal choice of an analgesic and antipyretic drug in paediatric practice |
| title_sort | optimal choice of an analgesic and antipyretic drug in paediatric practice |
| topic | fever in children pain syndrome in children nonsteroidal anti-inflammatory drugs paracetamol |
| url | https://www.med-sovet.pro/jour/article/view/2862 |
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