Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses

Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses

Abstract Background While almost all infants are infected with respiratory syncytial virus (RSV) before the age of 2 years, only a small percentage develops severe disease. Previous studies suggest that the nasopharyngeal microbiome affects disease development. We therefore studied the effect of the...

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Bibliographic Details
Main Authors: Thomas H. A. Ederveen, Gerben Ferwerda, Inge M. Ahout, Marloes Vissers, Ronald de Groot, Jos Boekhorst, Harro M. Timmerman, Martijn A. Huynen, Sacha A. F. T. van Hijum, Marien I. de Jonge
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Microbiome
Subjects:
Chemokine
Microbiome
Mucosal inflammation
RSV
Viral load
Online Access:http://link.springer.com/article/10.1186/s40168-017-0395-y

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