Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision
The purpose of the study was to investigate the long-term effects of uncomplicated phacoemulsification on macular perfusion using optical coherence tomography angiography (OCTA) in healthy aging subjects. OCTA was performed before phacoemulsification and 1 week, 1 month, 3 months, and 6 months after...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
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MDPI AG
2022-10-01
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| মালা: | Diagnostics |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://www.mdpi.com/2075-4418/12/10/2449 |
| _version_ | 1827650697737273344 |
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| author | Ana Ćurić Mirjana Bjeloš Mladen Bušić Biljana Kuzmanović Elabjer Benedict Rak Nenad Vukojević |
| author_facet | Ana Ćurić Mirjana Bjeloš Mladen Bušić Biljana Kuzmanović Elabjer Benedict Rak Nenad Vukojević |
| author_sort | Ana Ćurić |
| collection | DOAJ |
| description | The purpose of the study was to investigate the long-term effects of uncomplicated phacoemulsification on macular perfusion using optical coherence tomography angiography (OCTA) in healthy aging subjects. OCTA was performed before phacoemulsification and 1 week, 1 month, 3 months, and 6 months after. Superficial vascular complex (formed of nerve fiber layer vascular plexus and superficial vascular plexus), deep vascular complex (formed of intermediate capillary plexus and deep capillary plexus), as well as choriocapillaris (CC) and large choroidal blood vessels were recorded. Significant changes of vascular parameters in 95 eyes of 95 patients reached plateau 1 week after surgery and remained stable up to 6 months, occurring in all retinal layers but not in choroid and CC. Statistically significant increases in retinal vessels area, vessels percentage area, total number of junctions, junctions density, and total and average vessels length were found, followed by the total number of end points and mean lacunarity decline, proving an increase in blood supply. The study confirmed that uncomplicated phacoemulsification leads to a long-term increase in macular retinal perfusion. The results might ease the decision regarding timing for cataract surgery as long-term perfusion benefits can be achieved. Furthermore, study results provide a normative database of retinal and choroidal vasculature in healthy aging patients. |
| first_indexed | 2024-03-09T20:22:40Z |
| format | Article |
| id | doaj.art-c88928cfc0a340d184742c9a789cdbed |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T20:22:40Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-c88928cfc0a340d184742c9a789cdbed2023-11-23T23:45:30ZengMDPI AGDiagnostics2075-44182022-10-011210244910.3390/diagnostics12102449Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring VisionAna Ćurić0Mirjana Bjeloš1Mladen Bušić2Biljana Kuzmanović Elabjer3Benedict Rak4Nenad Vukojević5University Eye Department, Reference Centre of the Ministry of Health of the Republic of Croatia for Pediatric Ophthalmology and Strabismus, University Hospital “Sveti Duh”, Sveti Duh 64, 10000 Zagreb, CroatiaUniversity Eye Department, Reference Centre of the Ministry of Health of the Republic of Croatia for Pediatric Ophthalmology and Strabismus, University Hospital “Sveti Duh”, Sveti Duh 64, 10000 Zagreb, CroatiaUniversity Eye Department, Reference Centre of the Ministry of Health of the Republic of Croatia for Pediatric Ophthalmology and Strabismus, University Hospital “Sveti Duh”, Sveti Duh 64, 10000 Zagreb, CroatiaUniversity Eye Department, Reference Centre of the Ministry of Health of the Republic of Croatia for Pediatric Ophthalmology and Strabismus, University Hospital “Sveti Duh”, Sveti Duh 64, 10000 Zagreb, CroatiaUniversity Eye Department, Reference Centre of the Ministry of Health of the Republic of Croatia for Pediatric Ophthalmology and Strabismus, University Hospital “Sveti Duh”, Sveti Duh 64, 10000 Zagreb, CroatiaDepartment of Ophthalmology, University Hospital Centre Zagreb, 10000 Zagreb, CroatiaThe purpose of the study was to investigate the long-term effects of uncomplicated phacoemulsification on macular perfusion using optical coherence tomography angiography (OCTA) in healthy aging subjects. OCTA was performed before phacoemulsification and 1 week, 1 month, 3 months, and 6 months after. Superficial vascular complex (formed of nerve fiber layer vascular plexus and superficial vascular plexus), deep vascular complex (formed of intermediate capillary plexus and deep capillary plexus), as well as choriocapillaris (CC) and large choroidal blood vessels were recorded. Significant changes of vascular parameters in 95 eyes of 95 patients reached plateau 1 week after surgery and remained stable up to 6 months, occurring in all retinal layers but not in choroid and CC. Statistically significant increases in retinal vessels area, vessels percentage area, total number of junctions, junctions density, and total and average vessels length were found, followed by the total number of end points and mean lacunarity decline, proving an increase in blood supply. The study confirmed that uncomplicated phacoemulsification leads to a long-term increase in macular retinal perfusion. The results might ease the decision regarding timing for cataract surgery as long-term perfusion benefits can be achieved. Furthermore, study results provide a normative database of retinal and choroidal vasculature in healthy aging patients.https://www.mdpi.com/2075-4418/12/10/2449cataractretinal vesselshyperemiaphacoemulsificationintraocular pressure |
| spellingShingle | Ana Ćurić Mirjana Bjeloš Mladen Bušić Biljana Kuzmanović Elabjer Benedict Rak Nenad Vukojević Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision Diagnostics cataract retinal vessels hyperemia phacoemulsification intraocular pressure |
| title | Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision |
| title_full | Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision |
| title_fullStr | Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision |
| title_full_unstemmed | Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision |
| title_short | Long-Term Functional Hyperemia after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision |
| title_sort | long term functional hyperemia after uncomplicated phacoemulsification benefits beyond restoring vision |
| topic | cataract retinal vessels hyperemia phacoemulsification intraocular pressure |
| url | https://www.mdpi.com/2075-4418/12/10/2449 |
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