Transport Granules Bound with Nuclear Cap Binding Protein and Exon Junction Complex Are Associated with Microtubules and Spatially Separated from eIF4E Granules and P Bodies in Human Neuronal Processes

Transport Granules Bound with Nuclear Cap Binding Protein and Exon Junction Complex Are Associated with Microtubules and Spatially Separated from eIF4E Granules and P Bodies in Human Neuronal Processes

RNA transport and regulated local translation play critically important roles in spatially restricting gene expression in neurons. Heterogeneous population of RNA granules serve as motile units to translocate, store, translate, and degrade mRNAs in the dendrites contain cis-elements and trans-acting...

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Detalhes bibliográficos
Principais autores: Dan O. Wang, Kensuke Ninomiya, Chihiro Mori, Ayako Koyama, Martine Haan, Makoto Kitabatake, Masatoshi Hagiwara, Kazuhiro Chida, Shin-Ichiro Takahashi, Mutsuhito Ohno, Naoyuki Kataoka
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2017-12-01
coleção:Frontiers in Molecular Biosciences
Assuntos:
CBP80
Y14
exon junction complex
neuronal cells
RNA transport
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00093/full

Internet

http://journal.frontiersin.org/article/10.3389/fmolb.2017.00093/full

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