Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients
Introduction:Our study aims to evaluate the distribution of laryngopharyngeal reflux (LPR) in patients with sleep-disordered breathing (SDB) via the Reflux Symptom Index (RSI) and to describe the sleep architecture in SDB patients with and without LPR.Materials and Methods:A cross-sectional, descrip...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2022-11-01
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| Series: | Iranian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | https://ijorl.mums.ac.ir/article_21205_7c2207671c7aeac07ecd9a3cb516ed43.pdf |
| _version_ | 1827966561702379520 |
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| author | Elvie Rachmawati Retno Wardani Rahmanofa Yunizaf Saptawati Bardosono Fikri Putranto Niken Rizki Nabilla Calista Susyana Tamin |
| author_facet | Elvie Rachmawati Retno Wardani Rahmanofa Yunizaf Saptawati Bardosono Fikri Putranto Niken Rizki Nabilla Calista Susyana Tamin |
| author_sort | Elvie Rachmawati |
| collection | DOAJ |
| description | Introduction:Our study aims to evaluate the distribution of laryngopharyngeal reflux (LPR) in patients with sleep-disordered breathing (SDB) via the Reflux Symptom Index (RSI) and to describe the sleep architecture in SDB patients with and without LPR.Materials and Methods:A cross-sectional, descriptive study was conducted. Patients with SDB were identified via the Epworth Sleepiness Scale (ESS) and STOP-BANG questionnaire; they were then screened with the RSI and physical examination for LPR. PSG was performed to evaluate obstructive sleep apnea (OSA).Results:Of 45 patients, 15 were scored as having LPR via the RSI. Utilizing the Respiratory Disturbance Index (RDI), patients were further classified into four groups: 9 non-LPR with non-OSA SDB, 21 non-LPR with OSA, 4 LPR with non-OSA SDB, and 11 LPR with OSA. The prevalence of LPR was 30.8% in the non-OSA SDB group and 34.4% in the OSA group. All SDB parameters in both groups were similar. SDB patients with high body mass index tended to have LPR and/or OSA. Average ESS scores in the four groups suggested excessive daytime sleepiness, and patients with LPR had higher ESS scores. Regardless of LPR status, SDB patients had a lower percentage of REM sleep and a higher percentage of light sleep.Conclusions:The incidence of LPR in OSA patients was similar in non-OSA SDB patients. REM sleep percentage decreased in the four groups, with the non-OSA SDB group having the lowest percentage of REM sleep; light sleep percentage increased in the four groups, with the OSA group having the highest percentage of light sleep. |
| first_indexed | 2024-04-09T17:51:53Z |
| format | Article |
| id | doaj.art-c88af3daba634984931a29aa118c171f |
| institution | Directory Open Access Journal |
| issn | 2251-7251 2251-726X |
| language | English |
| last_indexed | 2024-04-09T17:51:53Z |
| publishDate | 2022-11-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Otorhinolaryngology |
| spelling | doaj.art-c88af3daba634984931a29aa118c171f2023-04-16T05:26:20ZengMashhad University of Medical SciencesIranian Journal of Otorhinolaryngology2251-72512251-726X2022-11-0134630331010.22038/ijorl.2022.57515.299121205Laryngopharyngeal Reflux in Sleep-Disordered Breathing PatientsElvie Rachmawati0Retno Wardani1Rahmanofa Yunizaf2Saptawati Bardosono3Fikri Putranto4Niken Rizki5Nabilla Calista6Susyana Tamin7Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hopsital, Jakarta, Indonesia.Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hopsital, Jakarta, Indonesia.Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hopsital, Jakarta, Indonesia.Department Nutrition, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Universitas Indonesia Hospital, Depok, Indonesia.Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hopsital, Jakarta, Indonesia.Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hopsital, Jakarta, Indonesia.Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hopsital, Jakarta, Indonesia.Introduction:Our study aims to evaluate the distribution of laryngopharyngeal reflux (LPR) in patients with sleep-disordered breathing (SDB) via the Reflux Symptom Index (RSI) and to describe the sleep architecture in SDB patients with and without LPR.Materials and Methods:A cross-sectional, descriptive study was conducted. Patients with SDB were identified via the Epworth Sleepiness Scale (ESS) and STOP-BANG questionnaire; they were then screened with the RSI and physical examination for LPR. PSG was performed to evaluate obstructive sleep apnea (OSA).Results:Of 45 patients, 15 were scored as having LPR via the RSI. Utilizing the Respiratory Disturbance Index (RDI), patients were further classified into four groups: 9 non-LPR with non-OSA SDB, 21 non-LPR with OSA, 4 LPR with non-OSA SDB, and 11 LPR with OSA. The prevalence of LPR was 30.8% in the non-OSA SDB group and 34.4% in the OSA group. All SDB parameters in both groups were similar. SDB patients with high body mass index tended to have LPR and/or OSA. Average ESS scores in the four groups suggested excessive daytime sleepiness, and patients with LPR had higher ESS scores. Regardless of LPR status, SDB patients had a lower percentage of REM sleep and a higher percentage of light sleep.Conclusions:The incidence of LPR in OSA patients was similar in non-OSA SDB patients. REM sleep percentage decreased in the four groups, with the non-OSA SDB group having the lowest percentage of REM sleep; light sleep percentage increased in the four groups, with the OSA group having the highest percentage of light sleep.https://ijorl.mums.ac.ir/article_21205_7c2207671c7aeac07ecd9a3cb516ed43.pdfapnea-hypopnea indexlaryngopharyngeal refluxnasolaryngopharyngeal endoscopyobstructive sleep apneareflux symptom index |
| spellingShingle | Elvie Rachmawati Retno Wardani Rahmanofa Yunizaf Saptawati Bardosono Fikri Putranto Niken Rizki Nabilla Calista Susyana Tamin Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients Iranian Journal of Otorhinolaryngology apnea-hypopnea index laryngopharyngeal reflux nasolaryngopharyngeal endoscopy obstructive sleep apnea reflux symptom index |
| title | Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients |
| title_full | Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients |
| title_fullStr | Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients |
| title_full_unstemmed | Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients |
| title_short | Laryngopharyngeal Reflux in Sleep-Disordered Breathing Patients |
| title_sort | laryngopharyngeal reflux in sleep disordered breathing patients |
| topic | apnea-hypopnea index laryngopharyngeal reflux nasolaryngopharyngeal endoscopy obstructive sleep apnea reflux symptom index |
| url | https://ijorl.mums.ac.ir/article_21205_7c2207671c7aeac07ecd9a3cb516ed43.pdf |
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