Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates
Streptokinase is a novel bacterial fibrinolytic enzyme that binds and activates plasminogen and is produced by several species of Streptococci. Streptococcus mutans was selected for optimum production of streptokinase using corn steep liquor, molasses, rice polishing and sugarcane bagass in liquid s...
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| Format: | Article |
| Language: | English |
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University of Agriculture, Faisalabad
2013-01-01
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| Series: | Pakistan Veterinary Journal |
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| Online Access: | http://pvj.com.pk/pdf-files/33_1/77-79.pdf |
| _version_ | 1828542260977860608 |
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| author | Muhammad Anjum Zia*, Rana Faisal, Rao Zahid Abbas1, Gull-e-Faran, Muhammad Kashif Saleemi2 and Junaid Ali Khan3 |
| author_facet | Muhammad Anjum Zia*, Rana Faisal, Rao Zahid Abbas1, Gull-e-Faran, Muhammad Kashif Saleemi2 and Junaid Ali Khan3 |
| author_sort | Muhammad Anjum Zia*, Rana Faisal, Rao Zahid Abbas1, Gull-e-Faran, Muhammad Kashif Saleemi2 and Junaid Ali Khan3 |
| collection | DOAJ |
| description | Streptokinase is a novel bacterial fibrinolytic enzyme that binds and activates plasminogen and is produced by several species of Streptococci. Streptococcus mutans was selected for optimum production of streptokinase using corn steep liquor, molasses, rice polishing and sugarcane bagass in liquid state fermentation. Substrates were applied in different concentrations ranging from 0.1-0.8%. Maximum fibrinolytic activity was observed by 0.3% corn steep liquor, 0.5% molasses and rice polishing and 0.4% by sugarcane bagass. The fibrinolytic activity achieved by fibrin clot lysis method was 5.5, 5.08, 5.16 and 4.75 units using corn steep liquor, molasses, rice polishing and sugarcane bagass, respectively. |
| first_indexed | 2024-12-12T01:52:51Z |
| format | Article |
| id | doaj.art-c88d550d730e4c88b8d56acd1d28f2ee |
| institution | Directory Open Access Journal |
| issn | 0253-8318 |
| language | English |
| last_indexed | 2024-12-12T01:52:51Z |
| publishDate | 2013-01-01 |
| publisher | University of Agriculture, Faisalabad |
| record_format | Article |
| series | Pakistan Veterinary Journal |
| spelling | doaj.art-c88d550d730e4c88b8d56acd1d28f2ee2022-12-22T00:42:26ZengUniversity of Agriculture, FaisalabadPakistan Veterinary Journal0253-83182013-01-013317779Comparison of Streptokinase Activity from Streptococcus mutans using Different SubstratesMuhammad Anjum Zia*, Rana Faisal, Rao Zahid Abbas1, Gull-e-Faran, Muhammad Kashif Saleemi2 and Junaid Ali Khan3Streptokinase is a novel bacterial fibrinolytic enzyme that binds and activates plasminogen and is produced by several species of Streptococci. Streptococcus mutans was selected for optimum production of streptokinase using corn steep liquor, molasses, rice polishing and sugarcane bagass in liquid state fermentation. Substrates were applied in different concentrations ranging from 0.1-0.8%. Maximum fibrinolytic activity was observed by 0.3% corn steep liquor, 0.5% molasses and rice polishing and 0.4% by sugarcane bagass. The fibrinolytic activity achieved by fibrin clot lysis method was 5.5, 5.08, 5.16 and 4.75 units using corn steep liquor, molasses, rice polishing and sugarcane bagass, respectively.http://pvj.com.pk/pdf-files/33_1/77-79.pdfCorn steep liquorStreptococcus mutansStreptokinaseSubstrates |
| spellingShingle | Muhammad Anjum Zia*, Rana Faisal, Rao Zahid Abbas1, Gull-e-Faran, Muhammad Kashif Saleemi2 and Junaid Ali Khan3 Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates Pakistan Veterinary Journal Corn steep liquor Streptococcus mutans Streptokinase Substrates |
| title | Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates |
| title_full | Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates |
| title_fullStr | Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates |
| title_full_unstemmed | Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates |
| title_short | Comparison of Streptokinase Activity from Streptococcus mutans using Different Substrates |
| title_sort | comparison of streptokinase activity from streptococcus mutans using different substrates |
| topic | Corn steep liquor Streptococcus mutans Streptokinase Substrates |
| url | http://pvj.com.pk/pdf-files/33_1/77-79.pdf |
| work_keys_str_mv | AT muhammadanjumziaranafaisalraozahidabbas1gullefaranmuhammadkashifsaleemi2andjunaidalikhan3 comparisonofstreptokinaseactivityfromstreptococcusmutansusingdifferentsubstrates |