An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications

An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications

The chemokine receptor 4 (CXCR4) is a promising diagnostic and therapeutic target for the management of various cancers. CXCR4 has been utilized in immunotherapy, targeted drug delivery, and endoradiotherapy. Poly(amidoamine) [PAMAM] dendrimers are well-defined polymers with unique properties that h...

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Bibliographic Details
Main Authors:	Wojciech G. Lesniak, Babak Behnam Azad, Samit Chatterjee, Ala Lisok, Martin G. Pomper
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Pharmaceutics
Subjects:	CXCR4 Indium-111 PAMAM dendrimer SPECT/CT POL3026 biodistribution
Online Access:	https://www.mdpi.com/1999-4923/14/3/655

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