Effects of bisphenol A and bisphenol analogs on the nervous system

Abstract. Estrogen impacts neural development; meanwhile, it has a protective effect on the brain. Bisphenols, primarily bisphenol A (BPA), can exert estrogen-like or estrogen-interfering effects by binding with estrogen receptors. Extensive studies have suggested that neurobehavioral problems, such...

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Main Authors: Chunxia Li, Chen Sang, Shuo Zhang, Sai Zhang, Hui Gao, Peng Lyu, Peifang Wei
Format: Article
Language:English
Published: Wolters Kluwer 2023-02-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002170
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author Chunxia Li
Chen Sang
Shuo Zhang
Sai Zhang
Hui Gao
Peng Lyu
Peifang Wei
author_facet Chunxia Li
Chen Sang
Shuo Zhang
Sai Zhang
Hui Gao
Peng Lyu
Peifang Wei
author_sort Chunxia Li
collection DOAJ
description Abstract. Estrogen impacts neural development; meanwhile, it has a protective effect on the brain. Bisphenols, primarily bisphenol A (BPA), can exert estrogen-like or estrogen-interfering effects by binding with estrogen receptors. Extensive studies have suggested that neurobehavioral problems, such as anxiety and depression, can be caused by exposure to BPA during neural development. Increasing attention has been paid to the effects on learning and memory of BPA exposure at different developmental stages and in adulthood. Further research is required to elucidate whether BPA increases the risk of neurodegenerative diseases and the underlying mechanisms, as well as to assess whether BPA analogs, such as bisphenol S and bisphenol F, influence the nervous system.
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spelling doaj.art-c8909e14d20444e3a619a1c777d4bc152023-04-24T10:06:47ZengWolters KluwerChinese Medical Journal0366-69992542-56412023-02-01136329530410.1097/CM9.0000000000002170202302050-00005Effects of bisphenol A and bisphenol analogs on the nervous systemChunxia LiChen SangShuo ZhangSai ZhangHui GaoPeng LyuPeifang WeiAbstract. Estrogen impacts neural development; meanwhile, it has a protective effect on the brain. Bisphenols, primarily bisphenol A (BPA), can exert estrogen-like or estrogen-interfering effects by binding with estrogen receptors. Extensive studies have suggested that neurobehavioral problems, such as anxiety and depression, can be caused by exposure to BPA during neural development. Increasing attention has been paid to the effects on learning and memory of BPA exposure at different developmental stages and in adulthood. Further research is required to elucidate whether BPA increases the risk of neurodegenerative diseases and the underlying mechanisms, as well as to assess whether BPA analogs, such as bisphenol S and bisphenol F, influence the nervous system.http://journals.lww.com/10.1097/CM9.0000000000002170
spellingShingle Chunxia Li
Chen Sang
Shuo Zhang
Sai Zhang
Hui Gao
Peng Lyu
Peifang Wei
Effects of bisphenol A and bisphenol analogs on the nervous system
Chinese Medical Journal
title Effects of bisphenol A and bisphenol analogs on the nervous system
title_full Effects of bisphenol A and bisphenol analogs on the nervous system
title_fullStr Effects of bisphenol A and bisphenol analogs on the nervous system
title_full_unstemmed Effects of bisphenol A and bisphenol analogs on the nervous system
title_short Effects of bisphenol A and bisphenol analogs on the nervous system
title_sort effects of bisphenol a and bisphenol analogs on the nervous system
url http://journals.lww.com/10.1097/CM9.0000000000002170
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