Development of a rabies virus-based retrograde tracer with high trans-monosynaptic efficiency by reshuffling glycoprotein

Abstract Rabies virus (RV) is the most widely used vector for mapping neural circuits. Previous studies have shown that the RV glycoprotein can be a target to improve the retrograde transsynaptic tracing efficiency. However, the current versions still label only a small portion of all presynaptic ne...

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Bibliographic Details
Main Authors: Fan Jia, Li Li, Haizhou Liu, Pei Lv, Xiangwei Shi, Yang Wu, Chen Ling, Fuqiang Xu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Brain
Online Access:https://doi.org/10.1186/s13041-021-00821-7