Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion
Background/Aim: Noonan syndrome (NS) is an autosomal dominant disorder, caused by mutations on genes located on the long arm of chromosome 12. The condition has no sex or race predilection and its incidence is 1 per 1,000 – 2,500 live births. Individuals affected with Noonan syndrome have distinctiv...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Balkan Stomatological Society
2020-07-01
|
| Series: | Balkan Journal of Dental Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/bjdm-2020-0020 |
| _version_ | 1811249280031129600 |
|---|---|
| author | Chatzistavrou Evangelia Andreadis Georgios |
| author_facet | Chatzistavrou Evangelia Andreadis Georgios |
| author_sort | Chatzistavrou Evangelia |
| collection | DOAJ |
| description | Background/Aim: Noonan syndrome (NS) is an autosomal dominant disorder, caused by mutations on genes located on the long arm of chromosome 12. The condition has no sex or race predilection and its incidence is 1 per 1,000 – 2,500 live births. Individuals affected with Noonan syndrome have distinctive facial features, hypertelorism, short stature, congenital heart disease; mainly pulmonary stenosis and hypertrophic cardiomyopathy, chest deformities, variable learning disabilities and mental retardation. Orofacial findings in Noonan syndrome may be high-arched palate, micrognathia, dental malocclusion and articulation difficulties. |
| first_indexed | 2024-04-12T15:43:40Z |
| format | Article |
| id | doaj.art-c894d08e0af146febccfc8096d373456 |
| institution | Directory Open Access Journal |
| issn | 2335-0245 |
| language | English |
| last_indexed | 2024-04-12T15:43:40Z |
| publishDate | 2020-07-01 |
| publisher | Balkan Stomatological Society |
| record_format | Article |
| series | Balkan Journal of Dental Medicine |
| spelling | doaj.art-c894d08e0af146febccfc8096d3734562022-12-22T03:26:43ZengBalkan Stomatological SocietyBalkan Journal of Dental Medicine2335-02452020-07-0124211812610.2478/bjdm-2020-0020bjdm-2020-0020Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the OcclusionChatzistavrou Evangelia0Andreadis Georgios1Private Practice, Thessaloniki, GreecePrivate Practice, Thessaloniki, GreeceBackground/Aim: Noonan syndrome (NS) is an autosomal dominant disorder, caused by mutations on genes located on the long arm of chromosome 12. The condition has no sex or race predilection and its incidence is 1 per 1,000 – 2,500 live births. Individuals affected with Noonan syndrome have distinctive facial features, hypertelorism, short stature, congenital heart disease; mainly pulmonary stenosis and hypertrophic cardiomyopathy, chest deformities, variable learning disabilities and mental retardation. Orofacial findings in Noonan syndrome may be high-arched palate, micrognathia, dental malocclusion and articulation difficulties.https://doi.org/10.2478/bjdm-2020-0020noonan syndromegenes mutationorthodonticspediatric dentistry |
| spellingShingle | Chatzistavrou Evangelia Andreadis Georgios Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion Balkan Journal of Dental Medicine noonan syndrome genes mutation orthodontics pediatric dentistry |
| title | Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion |
| title_full | Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion |
| title_fullStr | Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion |
| title_full_unstemmed | Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion |
| title_short | Noonan Syndrome in 12 -Year-Old Male: Case Report and Orthodontic Management of the Occlusion |
| title_sort | noonan syndrome in 12 year old male case report and orthodontic management of the occlusion |
| topic | noonan syndrome genes mutation orthodontics pediatric dentistry |
| url | https://doi.org/10.2478/bjdm-2020-0020 |
| work_keys_str_mv | AT chatzistavrouevangelia noonansyndromein12yearoldmalecasereportandorthodonticmanagementoftheocclusion AT andreadisgeorgios noonansyndromein12yearoldmalecasereportandorthodonticmanagementoftheocclusion |