Daam2 driven degradation of VHL promotes gliomagenesis
Von Hippel-Landau (VHL) protein is a potent tumor suppressor regulating numerous pathways that drive cancer, but mutations in VHL are restricted to limited subsets of malignancies. Here we identified a novel mechanism for VHL suppression in tumors that do not have inactivating mutations. Using devel...
| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
eLife Sciences Publications Ltd
2017-10-01
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| シリーズ: | eLife |
| 主題: | |
| オンライン･アクセス: | https://elifesciences.org/articles/31926 |