Mechanical stress induced mitochondrial dysfunction in cardiovascular diseases: Novel mechanisms and therapeutic targets

Mechanical stress induced mitochondrial dysfunction in cardiovascular diseases: Novel mechanisms and therapeutic targets

Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Others and our studies have shown that mechanical stresses (forces) including shear stress and cyclic stretch, occur in various pathological conditions, play significant roles in the development and progression of CVDs. Mit...

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Bibliographic Details
Main Authors: He Ren, Weiyi Hu, Tao Jiang, Qingping Yao, Yingxin Qi, Kai Huang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Mechanical stress
Mitochondrial dysfunction
Cardiovascular diseases (CVDs)
Energy metabolism
Reactive oxygen species (ROS)
Redox control
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224004293

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