Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators
Over the last couple of decades, stimuli-responsive supramolecular gels comprising synthetic short peptides as building blocks have been explored for various biological and material applications. Though a wide range of stimuli has been tested depending on the structure of the peptides, light as a st...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
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| Series: | Gels |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2310-2861/8/9/533 |
| _version_ | 1797488139790450688 |
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| author | Bapan Pramanik Sahnawaz Ahmed |
| author_facet | Bapan Pramanik Sahnawaz Ahmed |
| author_sort | Bapan Pramanik |
| collection | DOAJ |
| description | Over the last couple of decades, stimuli-responsive supramolecular gels comprising synthetic short peptides as building blocks have been explored for various biological and material applications. Though a wide range of stimuli has been tested depending on the structure of the peptides, light as a stimulus has attracted extensive attention due to its non-invasive, non-contaminant, and remotely controllable nature, precise spatial and temporal resolution, and wavelength tunability. The integration of molecular photo-switch and low-molecular-weight synthetic peptides may thus provide access to supramolecular self-assembled systems, notably supramolecular gels, which may be used to create dynamic, light-responsive “smart” materials with a variety of structures and functions. This short review summarizes the recent advancement in the area of light-sensitive peptide gelation. At first, a glimpse of commonly used molecular photo-switches is given, followed by a detailed description of their incorporation into peptide sequences to design light-responsive peptide gels and the mechanism of their action. Finally, the challenges and future perspectives for developing next-generation photo-responsive gels and materials are outlined. |
| first_indexed | 2024-03-09T23:58:45Z |
| format | Article |
| id | doaj.art-c8996868b485420cab35458195a24867 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-09T23:58:45Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-c8996868b485420cab35458195a248672023-11-23T16:21:39ZengMDPI AGGels2310-28612022-08-018953310.3390/gels8090533Peptide-Based Low Molecular Weight Photosensitive Supramolecular GelatorsBapan Pramanik0Sahnawaz Ahmed1Department of Chemistry, Ben-Gurion University of the Negev, Be’er Sheva 84105, IsraelDepartment of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research Kolkata, Kolkata 700054, IndiaOver the last couple of decades, stimuli-responsive supramolecular gels comprising synthetic short peptides as building blocks have been explored for various biological and material applications. Though a wide range of stimuli has been tested depending on the structure of the peptides, light as a stimulus has attracted extensive attention due to its non-invasive, non-contaminant, and remotely controllable nature, precise spatial and temporal resolution, and wavelength tunability. The integration of molecular photo-switch and low-molecular-weight synthetic peptides may thus provide access to supramolecular self-assembled systems, notably supramolecular gels, which may be used to create dynamic, light-responsive “smart” materials with a variety of structures and functions. This short review summarizes the recent advancement in the area of light-sensitive peptide gelation. At first, a glimpse of commonly used molecular photo-switches is given, followed by a detailed description of their incorporation into peptide sequences to design light-responsive peptide gels and the mechanism of their action. Finally, the challenges and future perspectives for developing next-generation photo-responsive gels and materials are outlined.https://www.mdpi.com/2310-2861/8/9/533peptidestimuli responsivegeltrans-cis isomerizationazobenzenearylazopyrozoles |
| spellingShingle | Bapan Pramanik Sahnawaz Ahmed Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators Gels peptide stimuli responsive gel trans-cis isomerization azobenzene arylazopyrozoles |
| title | Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators |
| title_full | Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators |
| title_fullStr | Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators |
| title_full_unstemmed | Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators |
| title_short | Peptide-Based Low Molecular Weight Photosensitive Supramolecular Gelators |
| title_sort | peptide based low molecular weight photosensitive supramolecular gelators |
| topic | peptide stimuli responsive gel trans-cis isomerization azobenzene arylazopyrozoles |
| url | https://www.mdpi.com/2310-2861/8/9/533 |
| work_keys_str_mv | AT bapanpramanik peptidebasedlowmolecularweightphotosensitivesupramoleculargelators AT sahnawazahmed peptidebasedlowmolecularweightphotosensitivesupramoleculargelators |