Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran.
Objective: Poor premorbid adjustment has been reported to be a predictor of more severe psychotic symptoms and poor quality of life in such psychotic disorders as schizophrenia. However, most studies were performed on chronic schizophrenic patients, and proposed the likelihood of recall bias...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2010-03-01
|
| Series: | Iranian Journal of Psychiatry |
| Subjects: | |
| Online Access: | https://ijps.tums.ac.ir/index.php/ijps/article/view/379 |
| _version_ | 1831539928203264000 |
|---|---|
| author | Javad Mahmoodi-Gharaei Anahita Basirnia Neda Abedi Behrang Shadloo Sara Jafari Niloofar Salesian Mohsen Djalali Vandad Sharifi |
| author_facet | Javad Mahmoodi-Gharaei Anahita Basirnia Neda Abedi Behrang Shadloo Sara Jafari Niloofar Salesian Mohsen Djalali Vandad Sharifi |
| author_sort | Javad Mahmoodi-Gharaei |
| collection | DOAJ |
| description | Objective: Poor premorbid adjustment has been reported to be a predictor of more severe psychotic symptoms and poor quality of life in such psychotic disorders as schizophrenia. However, most studies were performed on chronic schizophrenic patients, and proposed the likelihood of recall biases and the effect of chronicity. The aim of this study was to investigate these factors in a sample of first episode psychotic patients, as a part of Roozbeh first episode psychosis project (RooF).
Method: Premorbid adjustment was assessed using Premorbid Adjustment Scale (PAS) in 48 patients with the first psychotic episode who were admitted to Roozbeh Psychiatric Hospital. The severity of symptoms was measured using Positive and Negative Scale (PANSS) in three subgroups of positive, negative and general subscales. Quality of life was measured using WHO QOL ,and Global Assessment of Functioning (GAF) was also measured.
Results: The mean age was 24 years. Poor Premorbid adjustment in late adolescence was significantly associated with more severe symptoms according to PANSS negative symptoms (p=0.019, r=0.44). Furthermore, sociability and peer relationship domains had a positive correlation with PANSS negative subscale scores (r=0.531, p=0.002 and r=0.385, p=0.03, respectively). There were no significant differences between males and females in premorbid adjustment. Furthermore, this study failed to show any differences between affective and non-affective psychosis in premorbid functioning.
Conclusion: Our study confirms poor premorbid adjustment association with more severe negative symptoms and poor quality of life in a sample of Iranian first episode psychotic patients. |
| first_indexed | 2024-12-16T23:49:44Z |
| format | Article |
| id | doaj.art-c89a0b97b2b04c4eb27cb3c0f63a6b0f |
| institution | Directory Open Access Journal |
| issn | 1735-4587 2008-2215 |
| language | English |
| last_indexed | 2024-12-16T23:49:44Z |
| publishDate | 2010-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Psychiatry |
| spelling | doaj.art-c89a0b97b2b04c4eb27cb3c0f63a6b0f2022-12-21T22:11:23ZengTehran University of Medical SciencesIranian Journal of Psychiatry1735-45872008-22152010-03-0151Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran.Javad Mahmoodi-Gharaei0Anahita Basirnia1Neda Abedi2Behrang Shadloo3Sara Jafari4Niloofar Salesian5Mohsen Djalali6Vandad Sharifi7Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranRoozbeh Hospital, Psychiatry Department, Tehran University of Medical Sciences, Tehran, IranObjective: Poor premorbid adjustment has been reported to be a predictor of more severe psychotic symptoms and poor quality of life in such psychotic disorders as schizophrenia. However, most studies were performed on chronic schizophrenic patients, and proposed the likelihood of recall biases and the effect of chronicity. The aim of this study was to investigate these factors in a sample of first episode psychotic patients, as a part of Roozbeh first episode psychosis project (RooF). Method: Premorbid adjustment was assessed using Premorbid Adjustment Scale (PAS) in 48 patients with the first psychotic episode who were admitted to Roozbeh Psychiatric Hospital. The severity of symptoms was measured using Positive and Negative Scale (PANSS) in three subgroups of positive, negative and general subscales. Quality of life was measured using WHO QOL ,and Global Assessment of Functioning (GAF) was also measured. Results: The mean age was 24 years. Poor Premorbid adjustment in late adolescence was significantly associated with more severe symptoms according to PANSS negative symptoms (p=0.019, r=0.44). Furthermore, sociability and peer relationship domains had a positive correlation with PANSS negative subscale scores (r=0.531, p=0.002 and r=0.385, p=0.03, respectively). There were no significant differences between males and females in premorbid adjustment. Furthermore, this study failed to show any differences between affective and non-affective psychosis in premorbid functioning. Conclusion: Our study confirms poor premorbid adjustment association with more severe negative symptoms and poor quality of life in a sample of Iranian first episode psychotic patients.https://ijps.tums.ac.ir/index.php/ijps/article/view/379Psychological adaptationPsychotic disordersQuality of LifeRecovery of functionSymptoms |
| spellingShingle | Javad Mahmoodi-Gharaei Anahita Basirnia Neda Abedi Behrang Shadloo Sara Jafari Niloofar Salesian Mohsen Djalali Vandad Sharifi Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran. Iranian Journal of Psychiatry Psychological adaptation Psychotic disorders Quality of Life Recovery of function Symptoms |
| title | Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran. |
| title_full | Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran. |
| title_fullStr | Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran. |
| title_full_unstemmed | Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran. |
| title_short | Association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran, iran. |
| title_sort | association of premorbid adjustment with symptom profile and quality of life in first episode psychosis in a tertiary hospital in tehran iran |
| topic | Psychological adaptation Psychotic disorders Quality of Life Recovery of function Symptoms |
| url | https://ijps.tums.ac.ir/index.php/ijps/article/view/379 |
| work_keys_str_mv | AT javadmahmoodigharaei associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT anahitabasirnia associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT nedaabedi associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT behrangshadloo associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT sarajafari associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT niloofarsalesian associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT mohsendjalali associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran AT vandadsharifi associationofpremorbidadjustmentwithsymptomprofileandqualityoflifeinfirstepisodepsychosisinatertiaryhospitalintehraniran |