Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction
Introduction: The National Institute of Health defined ‘erectile dysfunction’ as the persistent inability to achieve and/or to maintain an erection for a satisfactory sexual performance. In last few years, the concept of erectile dysfunction has evolved from that of a disorder referred to as ‘im...
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JCDR Research and Publications Private Limited
2017-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/9270/25092_CE[Ra1]_F(DK)_PF1(RB_DK)_PFA(DK)_PF2(SH_DK).pdf |
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| author | Phani Chakravarty Mutnuru Harshavardhana Kurubara Manjaneyulu Rammurti Susarla Jyotsna Yarlagadda Rahul Devraj Prabakaran Palanisamy |
| author_facet | Phani Chakravarty Mutnuru Harshavardhana Kurubara Manjaneyulu Rammurti Susarla Jyotsna Yarlagadda Rahul Devraj Prabakaran Palanisamy |
| author_sort | Phani Chakravarty Mutnuru |
| collection | DOAJ |
| description | Introduction: The National Institute of Health defined ‘erectile
dysfunction’ as the persistent inability to achieve and/or to
maintain an erection for a satisfactory sexual performance. In
last few years, the concept of erectile dysfunction has evolved
from that of a disorder referred to as ‘impotence’ which used to
be considered predominantly psychogenic to that of ‘Erectile
Dysfunction’ (ED), a well understood physiologic result of
multiple risk factors, both psychological and organic. The most
common cause of organic erectile dysfunction is vasculogenic
causes. Doppler evaluation of cavernosal arteries after intracavernosal injection of Papaverine is particularly useful in the
evaluation of vasculogenic causes.
Aim: To define the role of intracavernosal injection of Papaverine
in the evaluation of vasculogenic causes of erectile dysfunction
that includes arterial insufficiency and veno occlusive nature.
Materials and Methods: Pharmaco Penile Duplex Ultrasonography (PPDU) was done using a linear broadband phased
array transducer (7–12 MHz) on a E-Saote MyLab 60 ultrasound
colour Doppler system on 73 patients over a period of three
years. Informed consent was taken from all patients. Visual
grading score for erection, Cavernosal Artery Diameter (CAD),
PSV (Peak Systolic Velocity), EDV (End Diastolic Velocity),
RI (Resistive Index), AT (Acceleration Time) and dorsal vein
changes were obtained in all patients following intracavernosal
injection of Papaverine.
Results: Visual grading for erectile response was E0 in one
patient, E1 in 11 patients, E2 in 9 patients, E3 in 7 patients,
E4 in 4 patients and E5 in 41 patients. Eighteen patients were
diagnosed as having arterial insufficiency, three patients were
diagnosed as having venous insufficiency and two patients
showed indeterminate results.
Conclusion: In our study, Papaverine induced PPDU proved to
be highly accurate and excellent method for assessing patients
with erectile dysfunction. |
| first_indexed | 2024-12-20T04:48:15Z |
| format | Article |
| id | doaj.art-c89cc044738647d08b58e30ecba12369 |
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| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-20T04:48:15Z |
| publishDate | 2017-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-c89cc044738647d08b58e30ecba123692022-12-21T19:52:55ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-01-01111TC07TC1010.7860/JCDR/2017/25092.9270Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile DysfunctionPhani Chakravarty Mutnuru0Harshavardhana Kurubara Manjaneyulu1Rammurti Susarla2Jyotsna Yarlagadda3Rahul Devraj4Prabakaran Palanisamy5Assistant Professor, Department of Radiology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India.Assistant Professor, Department of Radiology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.Professor and Head, Department of Radiology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.Professor, Department of Radiology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.Associate Professor, Department of Urology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.Ex Resident, Department of Radiology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.Introduction: The National Institute of Health defined ‘erectile dysfunction’ as the persistent inability to achieve and/or to maintain an erection for a satisfactory sexual performance. In last few years, the concept of erectile dysfunction has evolved from that of a disorder referred to as ‘impotence’ which used to be considered predominantly psychogenic to that of ‘Erectile Dysfunction’ (ED), a well understood physiologic result of multiple risk factors, both psychological and organic. The most common cause of organic erectile dysfunction is vasculogenic causes. Doppler evaluation of cavernosal arteries after intracavernosal injection of Papaverine is particularly useful in the evaluation of vasculogenic causes. Aim: To define the role of intracavernosal injection of Papaverine in the evaluation of vasculogenic causes of erectile dysfunction that includes arterial insufficiency and veno occlusive nature. Materials and Methods: Pharmaco Penile Duplex Ultrasonography (PPDU) was done using a linear broadband phased array transducer (7–12 MHz) on a E-Saote MyLab 60 ultrasound colour Doppler system on 73 patients over a period of three years. Informed consent was taken from all patients. Visual grading score for erection, Cavernosal Artery Diameter (CAD), PSV (Peak Systolic Velocity), EDV (End Diastolic Velocity), RI (Resistive Index), AT (Acceleration Time) and dorsal vein changes were obtained in all patients following intracavernosal injection of Papaverine. Results: Visual grading for erectile response was E0 in one patient, E1 in 11 patients, E2 in 9 patients, E3 in 7 patients, E4 in 4 patients and E5 in 41 patients. Eighteen patients were diagnosed as having arterial insufficiency, three patients were diagnosed as having venous insufficiency and two patients showed indeterminate results. Conclusion: In our study, Papaverine induced PPDU proved to be highly accurate and excellent method for assessing patients with erectile dysfunction.https://jcdr.net/articles/PDF/9270/25092_CE[Ra1]_F(DK)_PF1(RB_DK)_PFA(DK)_PF2(SH_DK).pdfimpotencepapaverinepenile doppler |
| spellingShingle | Phani Chakravarty Mutnuru Harshavardhana Kurubara Manjaneyulu Rammurti Susarla Jyotsna Yarlagadda Rahul Devraj Prabakaran Palanisamy Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction Journal of Clinical and Diagnostic Research impotence papaverine penile doppler |
| title | Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction |
| title_full | Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction |
| title_fullStr | Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction |
| title_full_unstemmed | Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction |
| title_short | Pharmaco Penile Duplex Ultrasonography in the Evaluation of Erectile Dysfunction |
| title_sort | pharmaco penile duplex ultrasonography in the evaluation of erectile dysfunction |
| topic | impotence papaverine penile doppler |
| url | https://jcdr.net/articles/PDF/9270/25092_CE[Ra1]_F(DK)_PF1(RB_DK)_PFA(DK)_PF2(SH_DK).pdf |
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