Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?

Background Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. Materials and M...

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Bibliographic Details
Main Authors: Nafiye Yilmaz, Ebru Ersoy, Aytekin Tokmak, Ayla Sargin, A. Seval Ozgu-Erdinc, Salim Erkaya, Halil Ibrahim Yakut
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2018-07-01
Series:International Journal of Fertility and Sterility
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Online Access:http://www.ijfs.ir/article_45485_3d9f7a24a78366721564bc2f48062662.pdf
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Summary:Background Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. Materials and Methods One hundred and four infertile and one hundred and three fertile women were recruited in this cross-sectional study which was conducted in a tertiary level maternity hospital. Infertile patients were divided into pregnant and non-pregnant subgroups after treatment. Individual characteristics and 25-hydroxyvitamin D3[25 (OH) D3] levels were compared between the groups. Results The vast majority of our study population consisted of women who had vitamin D deficiency (96.6%). There was no statistically significant difference between infertile and fertile groups in terms of serum 25 (OH) D3lev- els (P=0.512). Similarly, no significant difference was observed between the pregnant and non-pregnant subgroups of infertile patients regarding 25 (OH) D3levels (P=0.267). Conclusion There is no association between female infertility and serum vitamin D levels. Vitamin D does not pre- dict pregnancy in infertile women undergoing OI with IUI. Further research which will provide a comparison between much more women who have deficient and sufficient 25 (OH) D3levels is warranted.
ISSN:2008-076X
2008-0778