Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?

Background Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. Materials and M...

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Main Authors: Nafiye Yilmaz, Ebru Ersoy, Aytekin Tokmak, Ayla Sargin, A. Seval Ozgu-Erdinc, Salim Erkaya, Halil Ibrahim Yakut
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2018-07-01
Series:International Journal of Fertility and Sterility
Subjects:
Online Access:http://www.ijfs.ir/article_45485_3d9f7a24a78366721564bc2f48062662.pdf
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author Nafiye Yilmaz
Ebru Ersoy
Aytekin Tokmak
Ayla Sargin
A. Seval Ozgu-Erdinc
Salim Erkaya
Halil Ibrahim Yakut
author_facet Nafiye Yilmaz
Ebru Ersoy
Aytekin Tokmak
Ayla Sargin
A. Seval Ozgu-Erdinc
Salim Erkaya
Halil Ibrahim Yakut
author_sort Nafiye Yilmaz
collection DOAJ
description Background Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. Materials and Methods One hundred and four infertile and one hundred and three fertile women were recruited in this cross-sectional study which was conducted in a tertiary level maternity hospital. Infertile patients were divided into pregnant and non-pregnant subgroups after treatment. Individual characteristics and 25-hydroxyvitamin D3[25 (OH) D3] levels were compared between the groups. Results The vast majority of our study population consisted of women who had vitamin D deficiency (96.6%). There was no statistically significant difference between infertile and fertile groups in terms of serum 25 (OH) D3lev- els (P=0.512). Similarly, no significant difference was observed between the pregnant and non-pregnant subgroups of infertile patients regarding 25 (OH) D3levels (P=0.267). Conclusion There is no association between female infertility and serum vitamin D levels. Vitamin D does not pre- dict pregnancy in infertile women undergoing OI with IUI. Further research which will provide a comparison between much more women who have deficient and sufficient 25 (OH) D3levels is warranted.
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spelling doaj.art-c89d05e732804728b47006f2101567c72022-12-22T01:21:36ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782018-07-0112216416810.22074/ijfs.2018.525645485Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?Nafiye Yilmaz0Ebru Ersoy1Aytekin Tokmak2Ayla Sargin3A. Seval Ozgu-Erdinc4Salim Erkaya5Halil Ibrahim Yakut6Department of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyDepartment of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyDepartment of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyDepartment of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyDepartment of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyDepartment of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, TurkeyBackground Recent studies have shown that vitamin D has an essential role in the reproductive system. In this study, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), and subsequent intrauterine insemination (IUI) procedure. Materials and Methods One hundred and four infertile and one hundred and three fertile women were recruited in this cross-sectional study which was conducted in a tertiary level maternity hospital. Infertile patients were divided into pregnant and non-pregnant subgroups after treatment. Individual characteristics and 25-hydroxyvitamin D3[25 (OH) D3] levels were compared between the groups. Results The vast majority of our study population consisted of women who had vitamin D deficiency (96.6%). There was no statistically significant difference between infertile and fertile groups in terms of serum 25 (OH) D3lev- els (P=0.512). Similarly, no significant difference was observed between the pregnant and non-pregnant subgroups of infertile patients regarding 25 (OH) D3levels (P=0.267). Conclusion There is no association between female infertility and serum vitamin D levels. Vitamin D does not pre- dict pregnancy in infertile women undergoing OI with IUI. Further research which will provide a comparison between much more women who have deficient and sufficient 25 (OH) D3levels is warranted.http://www.ijfs.ir/article_45485_3d9f7a24a78366721564bc2f48062662.pdfinfertilityintrauterine inseminationovulation inductionvitamin d
spellingShingle Nafiye Yilmaz
Ebru Ersoy
Aytekin Tokmak
Ayla Sargin
A. Seval Ozgu-Erdinc
Salim Erkaya
Halil Ibrahim Yakut
Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?
International Journal of Fertility and Sterility
infertility
intrauterine insemination
ovulation induction
vitamin d
title Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?
title_full Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?
title_fullStr Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?
title_full_unstemmed Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?
title_short Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?
title_sort do serum vitamin d levels have any effect on intrauterine insemination success
topic infertility
intrauterine insemination
ovulation induction
vitamin d
url http://www.ijfs.ir/article_45485_3d9f7a24a78366721564bc2f48062662.pdf
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