Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review
Histoplasmosis is the most prevalent endemic mycosis on the American continent. It is caused by the dimorphic fungi Histoplasma spp. The infection is acquired by inhaling microconidia. It regularly starts in the lungs and then spreads to different organs. Skin involvement only occurs in 10% of cases...
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| Format: | Article |
| Language: | English |
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Permanyer
2017-07-01
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| Series: | Revista Médica del Hospital General de México |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0185106316300439 |
| _version_ | 1828471573772763136 |
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| author | Dyanne N. De la Rosa Mayron D. Nakandakari Jorge Gutiérrez-Gutiérrez Walter Bryson-Malca |
| author_facet | Dyanne N. De la Rosa Mayron D. Nakandakari Jorge Gutiérrez-Gutiérrez Walter Bryson-Malca |
| author_sort | Dyanne N. De la Rosa |
| collection | DOAJ |
| description | Histoplasmosis is the most prevalent endemic mycosis on the American continent. It is caused by the dimorphic fungi Histoplasma spp. The infection is acquired by inhaling microconidia. It regularly starts in the lungs and then spreads to different organs. Skin involvement only occurs in 10% of cases. We present the case of a patient with a history of alcoholism. The disease initially manifested with non-specific respiratory symptoms such as cough with bloody sputum, dyspnoea, fever and multiple skin lesions. Using the PAS (periodic acid–Schiff) and Grocott stain histochemical techniques, the skin biopsy revealed intracellular microorganisms with peripheral nuclei and perinuclear ring, identified as Histoplasma capsulatum. The spread of primary pulmonary histoplasmosis led to the presentation of skin lesions. Correct diagnosis and treatment in this case helped to reduce the high mortality of the disease. |
| first_indexed | 2024-12-11T05:14:29Z |
| format | Article |
| id | doaj.art-c89e6f1b7d7041c4b3098a63899fead3 |
| institution | Directory Open Access Journal |
| issn | 0185-1063 |
| language | English |
| last_indexed | 2024-12-11T05:14:29Z |
| publishDate | 2017-07-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Revista Médica del Hospital General de México |
| spelling | doaj.art-c89e6f1b7d7041c4b3098a63899fead32022-12-22T01:19:51ZengPermanyerRevista Médica del Hospital General de México0185-10632017-07-0180317017310.1016/j.hgmx.2016.05.013Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature reviewDyanne N. De la Rosa0Mayron D. Nakandakari1Jorge Gutiérrez-Gutiérrez2Walter Bryson-Malca3Human Medicine Student, Universidad Privada San Juan Bautista, Lima, PeruHuman Medicine Student, Universidad Privada San Juan Bautista, Lima, PeruPulmonologist, Department of Pulmonology, Hospital Nacional Hipólito Unanue, Lima, PeruIntensive Care Specialist, Intensive Care Unit, Hospital Nacional Hipólito Unanue, Lima, PeruHistoplasmosis is the most prevalent endemic mycosis on the American continent. It is caused by the dimorphic fungi Histoplasma spp. The infection is acquired by inhaling microconidia. It regularly starts in the lungs and then spreads to different organs. Skin involvement only occurs in 10% of cases. We present the case of a patient with a history of alcoholism. The disease initially manifested with non-specific respiratory symptoms such as cough with bloody sputum, dyspnoea, fever and multiple skin lesions. Using the PAS (periodic acid–Schiff) and Grocott stain histochemical techniques, the skin biopsy revealed intracellular microorganisms with peripheral nuclei and perinuclear ring, identified as Histoplasma capsulatum. The spread of primary pulmonary histoplasmosis led to the presentation of skin lesions. Correct diagnosis and treatment in this case helped to reduce the high mortality of the disease.http://www.sciencedirect.com/science/article/pii/S0185106316300439HistoplasmosisDeep mycosisImmunosuppressionAlcoholism |
| spellingShingle | Dyanne N. De la Rosa Mayron D. Nakandakari Jorge Gutiérrez-Gutiérrez Walter Bryson-Malca Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review Revista Médica del Hospital General de México Histoplasmosis Deep mycosis Immunosuppression Alcoholism |
| title | Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review |
| title_full | Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review |
| title_fullStr | Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review |
| title_full_unstemmed | Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review |
| title_short | Disseminated pulmonary histoplasmosis with multiple cutaneous lesions: Case report and literature review |
| title_sort | disseminated pulmonary histoplasmosis with multiple cutaneous lesions case report and literature review |
| topic | Histoplasmosis Deep mycosis Immunosuppression Alcoholism |
| url | http://www.sciencedirect.com/science/article/pii/S0185106316300439 |
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