NAC Pre-Administration Prevents Cardiac Mitochondrial Bioenergetics, Dynamics, Biogenesis, and Redox Alteration in Folic Acid-AKI-Induced Cardio-Renal Syndrome Type 3

NAC Pre-Administration Prevents Cardiac Mitochondrial Bioenergetics, Dynamics, Biogenesis, and Redox Alteration in Folic Acid-AKI-Induced Cardio-Renal Syndrome Type 3

The incidence of kidney disease is increasing worldwide. Acute kidney injury (AKI) can strongly favor cardio-renal syndrome (CRS) type 3 development. However, the mechanism involved in CRS development is not entirely understood. In this sense, mitochondrial impairment in both organs has become a cen...

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Main Authors: Belén Cuevas-López, Edgar Ignacio Romero-Ramirez, Fernando E. García-Arroyo, Edilia Tapia, Juan Carlos León-Contreras, Alejandro Silva-Palacios, Francisco-Javier Roldán, Omar Noel Medina Campos, Luz Hernandez-Esquivel, Alvaro Marín-Hernández, José Guillermo Gonzaga-Sánchez, Rogelio Hernández-Pando, José Pedraza-Chaverri, Laura Gabriela Sánchez-Lozada, Omar Emiliano Aparicio-Trejo
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Antioxidants
Subjects:
cardio-renal syndrome type 3
folic acid-induced cardio-renal damage
NAC and mitochondria
mitochondrial ROS production
mitochondrial dynamic
biogenesis
Online Access:https://www.mdpi.com/2076-3921/12/8/1592

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