Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells

Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells

Background/Aims: Osteosarcoma is the predominant form of primary bone malignancy. Although the combinational application of neoadjuvant chemotherapy and surgical resection significantly increases the survival rate, the therapeutic outcome remains unsatisfactory. Deoxyelephantopin (DET), an active in...

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Bibliographic Details
Main Authors: Jilong Zou, Yan Zhang, Jiabing Sun, Xiaoyan Wang, Hualei Tu, Shuo Geng, Renhao Liu, Yuxi Chen, Zhenggang Bi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Deoxyelephantopin
Apoptosis
Autophagy
ROS
Osteosarcoma
Proliferation
Online Access:http://www.karger.com/Article/FullText/479537

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